A significant pathway for the reactions between Grignard reagents and ketones: Single electron transfer process

Abstract

A review with 24 refs. The generally accepted mechanisms for the Grignard reactions of ketones are described. Evidences supporting the single electron transfer (SET) process in some of the reactions under certain conditions are presented. Some main factors, including structure of reactants, nature of solvents and effect of transition-metal impurities, which might affect the course and mechanism (ionic and/or SET) of the reactions are also discussed.6

Key words: REACTION MECHANISM, KETONE, ELECTRON TRANSITION, GRIGNARD REAGENT

CLC Number:

O621.16

Cite this article

GONG YUEFA;ZHAO CHENGXUE. A significant pathway for the reactions between Grignard reagents and ketones: Single electron transfer process[J]. Chin. J. Org. Chem., 1988, 8(6): 481-486.

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