Chin. J. Org. Chem. ›› 1989, Vol. 9 ›› Issue (3): 242-246. Previous Articles     Next Articles

钩吻素子合成方法的研究 II: 异喹宁环体系烯丙位的氧化反应

王志勤;骆益麟   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1989-06-25

Studies on the synthetic approach of koumine II: Allylic oxidation of isoquinuclidine derivatives

WANG ZHIQIN;LUO YILIN   

  • Published:1989-06-25

Allylic oxidation of isoquinuclidine I (R = Et) has been performed by using chromic oxide-pyridine complex as oxidant. The stereochem. of the acetyl group of ketone II formed by the hydrogenation of I (R = COMe) has been proved to be cis to the C-carbomethoxy group.

Key words: ALKALOID, OXIDATION, INFRARED SPECTROPHOTOMETRY, NITROGEN HETEROCYCLICS, GELSEMIUM ELEGANS, BRIDGE COMPOUNDS, POLYCARBOXYLIC ACID, KOUMINE, BICYCLOOCTANE P

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