Chin. J. Org. Chem. ›› 1992, Vol. 12 ›› Issue (5): 488-491. Previous Articles     Next Articles

Original Articles

手性胶束中的不对称Micheal反主尖

张承敏;方向红;王淑群   

  1. 杭州大学化学系
  • 发布日期:1992-10-25

Asymmetric michael reaction in chiral micellar systems

ZHANG CHENGMIN;FANG XIANGHONG;WANG SHUQUN   

  • Published:1992-10-25

In aqueous micelles formed from the chiral surfactants N-dodecyl-N,N-dimethylephedrine bromide and N-hexadecyl-N,N-dimethylephedrine bromide, a series of optical active products were obtained by Michael addition of nitromethane or thiophenol to chalcones I (R = H, 2-Br, 4-Br, 4-NO2, 4-MeO) using piperine as catalyst, the enantiomer excess was up to 17 %. The micellar system also accelerated the Michael reaction.

Key words: THIOPHENOLS, CHALCONE, MICHAEL CONDENSATION REACTION, NITROCARBOL

CLC Number: