Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (2): 470-477.DOI: 10.6023/cjoc201905034 Previous Articles     Next Articles


李莎, 徐嘉煜, 罗鲜, 杨雯涵, 姚昌盛   

  1. 江苏省功能材料绿色合成重点实验室 江苏师范大学化学与材料科学学院 徐州 221116
  • 收稿日期:2019-05-14 修回日期:2019-09-19 发布日期:2019-10-09
  • 通讯作者: 姚昌盛
  • 基金资助:

Efficient N-Heterocyclic Carbene-Catalyzed Cascade Synthesis of Functionalized Naphthopyranone

Li Sha, Xu Jiayu, Luo Xian, Yang Wenhan, Yao Changsheng   

  1. Jiangsu Key Laboratory of Green Synthetic Chemistry for Functional Materials, School of Chemistry and Materials Science, Jiangsu Normal University, Xuzhou 221116
  • Received:2019-05-14 Revised:2019-09-19 Published:2019-10-09
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Nos. 21871113, 21372101).

An efficient N-heterocyclic carbene (NHC)-catalyzed "Michael-Michael-Lactonization" cascade process involving chalcone derivatives and α-bromoenals for the syntheses of functionalized naphthopyranones was disclosed. This approach was qualified with good yields, readily available starting materials and mild reaction conditions.

Key words: N-heterocyclic carbene (NHC), α-bromoenals, chalcone derivatives, functionalized naphthopyranone, cascade reaction