Chin. J. Org. Chem. ›› 1994, Vol. 14 ›› Issue (4): 427-429. Previous Articles     Next Articles

Original Articles

(+)-2-甲基-4-戊烯酸的合成

黄锦霞;陈家威;潘贻军;岳霞丽   

  1. 湖北大学化学系;华中农业大学化学组
  • 发布日期:1994-08-25

Synthesis of (+)-2-methyl-4-amylenic acid

HUANG JINXIA;CHEN JIAWEI;PAN YIJUN   

  • Published:1994-08-25

Diethyl malonate reacted with iodomethane to give diethyl methylmalonate(1). 2-methyl-4-amylenic acid (4) was prepared by saponification and decarboxylation of (1). Resolution of (4) with glucose caprylamine, a new resolution agent, give (+)-2-methyl-4-amylenic acid (5).

Key words: SAPONIFICATION, MESOTOMY, DECARBOXYLATION, ETHYLENE GLYCOL MALONATE, PENTENOIC ACID P

CLC Number: