Chin. J. Org. Chem. ›› 1994, Vol. 14 ›› Issue (5): 521-525. Previous Articles     Next Articles

Original Articles

N'-(4,5,6-三取代嘧啶-2-基)-2-噻吩磺酰脲的合成

薛思佳;张爱东;万树青;刘钊杰   

  1. 华中师范大学化学系;华中师范大学有机合成研究所
  • 发布日期:1994-10-25

Synthesis of N'-(4,5,6-trisubstitutedpyrimidin-2-ly)-2- thiophenesulfonylureas

XUE SIJIA;ZHANG AIDONG;WAN SHUQING;LIU ZHAOJIE   

  • Published:1994-10-25

Thirteen title compounds (5a~5m) were synthesized by nucleophilic addition of 2-amino-4,5,6-trisubstitutedpyrimidines and 2-thiophenesulfonyl isocyanate in good yields. Their structures were proved by ^1H NMR, IR and elementary analysis and their biologically activities were tested.

Key words: ISOCYANATE P, BIOLOGICAL ACTIVITY, SULFONYLUREA

CLC Number: