Chin. J. Org. Chem. ›› 2000, Vol. 20 ›› Issue (3): 388-390. Previous Articles     Next Articles

酶促法还原β-酮砜合成粉蠹虫性信息素

李焰;陈祖兴;石从云   

  1. 湖北大学化学与材料科学学院
  • 发布日期:2000-06-25

Synthesis of S-(+)-sulcatol by enzymatic reduction of β - ketosulfone

Li Yan;Chen Zuxing;Shi Congyun   

  • Published:2000-06-25

1-(4-Methyl)phenysulfonyl-2-propanone was reduced with baker's yeast to a chiral alcohol 1-(4-methyl) phenylsulfonyl-2-propanol of very high optical purity. This alcohol was alkylated and desulfurated with Raney-Ni to the target compound (S)-(+)-6-methyl-5-heptene-2-ol. The enantiometric excess is 92%.

Key words: YEAST, REDUCTION, ALKYLATION, DESULFURIZATION, SEX PHEROMONE, ENZYMATIC, INSECT HORMONE

CLC Number: