Synthesis of Some New Monocyclic β-Lactams Containing 2-Phenyl-1,2,3-triazolyl

Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (9): 1129-1132. Previous Articles Next Articles

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含2-苯基-1,2,3-三唑基单环β-内酰胺类化合物的合成

阎琴¹，邵玲²，刘方明*^,1,3，解正峰¹，孙万赋¹，李锋¹

(¹新疆大学化学系乌鲁木齐 830046)
(²南开大学元素有机化学研究所天津 300071)
(³杭州师范学院化学系杭州 310012)

收稿日期:2004-01-13 修回日期:2004-04-01 发布日期:2005-08-24
通讯作者: 刘方明

Synthesis of Some New Monocyclic β-Lactams Containing 2-Phenyl-1,2,3-triazolyl

YAN Qin¹,SHAO Ling²,LIU Fang-Ming*^,1,3 XIE Zheng-Feng¹
SUN Wan-Fu¹,LI Feng¹

(¹ Department of Chemistry, Xinjiang University, Urumqi 830046)
(² Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071)
(³ Department of Chemistry, Hangzhou Teacher’s Col-lege, Hangzhou 310012)

Received:2004-01-13 Revised:2004-04-01 Published:2005-08-24
Contact: LIU Fang-Ming

Abstract

Ketene-imine cycloaddition is an efficient synthetic method for monocyclic β-lactams. Under heat and reflux in benzene, a solution of the phthaloylglycyl chloride was added to a solution of triethylamine and Schiff base containing 2-phenyl-1,2,3-triazolyl. The configurations of new monocyclic β-lactams are all-trans. The structure and configuration of the compounds were confirmed by elemental analysis, IR, ¹H NMR, MS and NOESY data.

Key words: 2-phenyl-1,2,3-triazolyl, cycloaddition, monocyclic β-lactam

Cite this article

YAN Qin,SHAO Ling²,LIU Fang-Ming*^,1,3 XIE Zheng-Feng
SUN Wan-Fu,LI Feng. Synthesis of Some New Monocyclic β-Lactams Containing 2-Phenyl-1,2,3-triazolyl[J]. Chin. J. Org. Chem., 2005, 25(9): 1129-1132.

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含2-苯基-1,2,3-三唑基单环β-内酰胺类化合物的合成

Synthesis of Some New Monocyclic β-Lactams Containing 2-Phenyl-1,2,3-triazolyl

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