Foldamer-Based Molecular Recognition

Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (02): 188-196. Previous Articles Next Articles

Review

基于非生物折叠体的分子识别

李昌治^a，蒋锡夔^b，黎占亭*^,b，高翔^a，王全瑞*^,a

(^a复旦大学化学系上海 200433)
(^b中国科学院上海有机化学研究所生命有机化学国家重点实验室上海 200032)

收稿日期:2005-09-14 修回日期:2006-06-19 发布日期:2007-01-30
通讯作者: 王全瑞

Foldamer-Based Molecular Recognition

LI Chang-Zhi^a, JIANG Xi-Kui^b, LI Zhan-Ting*^,b, GAO Xiang^a, WANG Quan-Rui*^,a

(^aDepartment of Chemistry, Fudan University, Shanghai 200433)
(^bState Key Laboratory of Bio-organic and Natural Products Chemistry, Shanghai Institute of Organic Chemis-try,
Chinese Academy of Sciences, Shanghai 200032)

Received:2005-09-14 Revised:2006-06-19 Published:2007-01-30
Contact: WANG Quan-Rui

Abstract

One of the challenging fields in physical organic chemistry is the control of the conformation of large linear organic molecules. In recent years, different non-covalent forces, especially hydrogen bonding and hydrophobic interaction, have been successfully applied to induce the folded or helical conformations of linear organic molecules. This paper reviews the recent applications of this new class of non-biological secondary structures in molecular recognition.

Key words: hydrogen bonding, hydrophobic interaction, secondary structure, molecular recognition, foldamer

Cite this article

LI Chang-Zhi^a, JIANG Xi-Kui^b, LI Zhan-Ting*^,b, GAO Xiang^a, WANG Quan-Rui*^,a. Foldamer-Based Molecular Recognition[J]. Chin. J. Org. Chem., 2007, 27(02): 188-196.

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基于非生物折叠体的分子识别

Foldamer-Based Molecular Recognition

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