Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (3): 614-624.DOI: 10.6023/cjoc201909029 Previous Articles     Next Articles


黄国保a, 陈志林a, 韦贤生a, 陈钰a, 李秀英a, 仲辉b, 谭明雄a   

  1. a 玉林师范学院化学与食品科学学院 广西农产资源化学与生物技术重点实验室 广西玉林 537000;
    b 中国药科大学中药学院中药药理系 南京 211100
  • 收稿日期:2019-09-18 修回日期:2019-10-31 发布日期:2020-04-02
  • 通讯作者: 仲辉, 谭明雄;
  • 基金资助:

Recent Progress on the Construction and Function of Macrocyclic Compounds Containing Hydrogen Bond Donors

Huang Guobaoa, Chen Zhilina, Wei Xianshenga, Chen Yua, Li Xiuyinga, Zhong Huib, Tan Mingxionga   

  1. a Guangxi Key Laboratory of Agricultural Resources Chemistry and Biotechnology, College of Chemistry and Food Science, Yulin Normal University, Yulin, Guangxi 537000;
    b School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 211100
  • Received:2019-09-18 Revised:2019-10-31 Published:2020-04-02
  • Supported by:
    Project supported by the National Natural Science Foundation of China (No. 21961042), the Natural Science Foundation of Guangxi Province (No. 2018GXNSFAA294064) and the Yulin Normal University Research Grant (Nos. 2018YJKY36, 201810606010).

Because of the N-H group structure in the macrocyclic compound containing hydrogen bond Donors, it can provide additional intermolecular forces in the host-guest chemistry, and this character is widely used in the molecular recognition, self-assembly, supramolecular catalysis and other fields. The recent progress on the synthetic methods of macrocyclic compounds based on (thio) urea, amide and its molecular recognition in 2010~2019 are summarized. It is hoped that this review can be referred to synthesis and applications of this kind of macrocyclic compounds.

Key words: hydrogen bond donor group, macrocyclic compounds, synthesis, molecular recognition