Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (04): 736-740. Previous Articles     Next Articles

Reports

N-(4,6-二取代嘧啶-2-基)-N'-[1-(杂芳基)甲基-5-甲基-1H-1,2,3-三唑基-4- 甲酰基]硫脲的合成与除草活性研究

严曼,石德清*   

  1. (华中师范大学化学学院 农药与化学生物学教育部重点实验室 武汉 430079)
  • 收稿日期:2007-07-11 修回日期:2007-10-11 发布日期:2008-04-17
  • 通讯作者: 石德清

Synthesis and Herbicidal Activity of N-(4,6-Disubstituted pyrimidin-2-yl)-N'-[1-(heteroaryl)methyl-5-methyl-1H-1,2,3-triazol-4-ylcarbonyl]thiourea

YAN Man,SHI De-Qing*   

  1. (Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry,
    Central China Normal University, Wuhan 430079)
  • Received:2007-07-11 Revised:2007-10-11 Published:2008-04-17
  • Contact: SHI De-Qing

In order to find novel low toxicity and potent herbicides, ten title compounds were synthesized by the multi-step reaction using 2-chloro-5-(chloromethyl)pyridine or 2-chloro-5-(chloromethyl)thiazole as starting materials. The structures of the target compounds were characterized by IR, 1H NMR, MS spectra and elemental analysis. Preliminary bioassays show that some of the target compounds possess good herbicidal activities against selected weeds at a concerntration of 100 mg/L.

Key words: thiazole, herbicidal activity, pyridine, 1,2,3-triazole, thiourea, pyrimidine