Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (05): 889-893. Previous Articles     Next Articles

Reports

新型双缩硫代对称二氨基脲类衍生物的合成和生物活性测试

孙亚栋a,解正峰*,a,刘方明*,b,陈家胜a   

  1. (a新疆大学化学与化工学院 乌鲁木齐 830046)
    (b杭州师范学院化学系 杭州 310012)
  • 收稿日期:2007-05-09 修回日期:2007-11-04 发布日期:2008-05-20
  • 通讯作者: 刘方明

Synthesis and Biological Activities of Novel Thiocarbohydrazone Derivatives

SUN Ya-Donga,XIE Zheng-Feng*,a,LIU Fang-Ming*,b,CHEN Jia-Shenga   

  1. (a College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046)
    (b Department of Chemistry, Hangzhou Teacher's College, Hangzhou 310012)
  • Received:2007-05-09 Revised:2007-11-04 Published:2008-05-20
  • Contact: LIU Fang-Ming

The condensation reaction of thiocarbohydrazide with ten substituted acetophenones containing triazole or benzotriazole moiety is described. Ten new N1,N5-bis[α-(1,2,3-trizaol-1-ylmethyl)-(un)substituted benzylidene]thiacarbohydrazide derivatives have been synthesized. Their structures were confirmed by ele-mental analysis, IR, 1H NMR, 13C NMR and MS spectra. The antifungal and antivirus activities of the new compounds have been tested.

Key words: benzotriazole, dithiocarbohydrazone, triazole