Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (2): 330-334. Previous Articles     Next Articles

Reports

5(6)-羧基荧光素标记2′-脱氧尿苷的合成

丁海新,万明,阳如春,肖伟洪,肖强*   

  1. (江西科技师范学院有机功能分子研究所 江西省有机功能分子重点实验室 南昌 330013)
  • 收稿日期:2007-05-14 修回日期:2007-07-20 发布日期:2008-02-01
  • 通讯作者: 肖强

Synthesis of 2'-Deoxyuridine Labeled with 5(6)-Carboxyfluorescein

DING Hai-Xin,WAN Ming,YANG Ru-Chun,XIAO Wei-Hong,XIAO Qiang*   

  1. (Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University, Nanchang 330013)
  • Received:2007-05-14 Revised:2007-07-20 Published:2008-02-01
  • Contact: XIAO Qiang

2'-Deoxyuridine labeled with 5(6)-carboxylfluorescein was synthesized in six steps from 5-iodo-2'-dexoyuridine. Their structures were analyzed and characterized using HPLC, 1H NMR and 13C NMR spectra.

Key words: 5(6)-carboxylfluorescein, 2'-deoxyuridine, fluorescence labeling, separation