Advances in Glycosyltransferase Inhibitors

Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (05): 703-715. Previous Articles Next Articles

Review

糖基转移酶抑制剂研究进展

陈华^a ; 王东跃^b ; 李小六^*,a

(a河北大学化学与环境科学院河北省化学生物学重点实验室教育部药物化学与分子诊断
省部共建重点实验室保定 071002)
(b河北农业大学理学院保定 071001)

收稿日期:2007-11-28 修回日期:2008-10-10 发布日期:2009-05-20
通讯作者: 李小六

Advances in Glycosyltransferase Inhibitors

Chen, Hua^a ; Wang, Dongyue^b; Li, Xiaoliu^*,a

(a Key Laboratory of Chemical Biology of Hebei Province, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, College of Chemistry and Environmental Science, Hebei University, Baoding 071002)
(b College of Science, Hebei Agricultural University, Baoding 071001)

Received:2007-11-28 Revised:2008-10-10 Published:2009-05-20
Contact: Li, Xiaoliu

Abstract

Glycosyltransferases play a pivotal role in the biosynthesis of oligosaccharides in glycoproteins and glycolipids. The glycosyltransferase inhibitors have the potential for discovering the drugs of anti-tumor, anti-diseases of immune system, etc. This review presents the recent progress in the study on the structure and biological activity of the synthesized glycosyltransferase inhibitors.

Key words: inhibitor, anti-tumor, anti-disease of immune system, glycosyltransferase

Cite this article

Chen, Hua^a ; Wang, Dongyue^b; Li, Xiaoliu^*,a. Advances in Glycosyltransferase Inhibitors[J]. Chin. J. Org. Chem., 2009, 29(05): 703-715.

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糖基转移酶抑制剂研究进展

Advances in Glycosyltransferase Inhibitors

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