Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (05): 784-787. Previous Articles     Next Articles

Reports

1,3-二苯基吡唑的脱氢合成

廖 勇 ; 黄文海 ; 胡纯琦 ; 胡永洲 ; 盛 荣*   

  1. (浙江大学药学院 浙江大学-巴黎高师药物化学联合实验室 杭州 310058)
  • 收稿日期:2008-07-08 修回日期:2008-11-06 发布日期:2009-05-20
  • 通讯作者: 盛 荣

Dehydrogenation Synthesis of 1,3-Diphenylpyrazoles

Liao, Yong ; Huang, Wenhai ; Hu, Chunqi; Hu, Yongzhou; Sheng, Rong*   

  1. (ZJU-ENS Joint Laboratory of Medicinal Chemistry School of Pharmaceutical Sciences, Zhejiang University,
    Hangzhou 310058)
  • Received:2008-07-08 Revised:2008-11-06 Published:2009-05-20
  • Contact: Sheng, Rong

A series of 1,3-diphenylpyrazole derivatives were synthesized from substituted 1,3-diphenyl- pyrazolines with potassium permanganate supported on silica gel as dehydrogenation reagent at room temperature. The reactions were easily worked up with high yields under mild conditions.

Key words: 1,3-diphenylpyrazoline, 1,3-diphenylpyrazole, potassium permanganate supported on silica gel, dehydrogenati