Stereospecific Synthesis of (2S,4S)/(2S,4R)-4-Fluoroglutamic Acids Base on Natural Chiral Source (4R)-Hydroxyproline

Chin. J. Org. Chem. ›› 2010, Vol. 30 ›› Issue (12): 1931-1934. Previous Articles Next Articles

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基于同一天然手性源(4R)-羟基脯氨酸的(2S,4S)/(2S,4R)-4-氟谷氨酸的立体专一性合成

李春雷¹，王衍超²，谭瑛英²^{,3，李硕*^{,2，杨中铎*^,3,4}}

(¹兰州理工大学石油化工学院兰州 730050)
(²北京大学深圳研究生院化学生物学与生物技术学院化学基因组学深圳 518055)
(³兰州理工大学生命科学与工程学院兰州 730050)
(⁴功能有机分子化学国家重点实验室(兰州大学) 兰州 730000)

收稿日期:2009-11-27 修回日期:2010-05-14 发布日期:2010-07-12
通讯作者: 杨中铎 E-mail:yangzhongduo@126.com

Stereospecific Synthesis of (2S,4S)/(2S,4R)-4-Fluoroglutamic Acids Base on Natural Chiral Source (4R)-Hydroxyproline

Li Chunlei¹ Wang Yanchao² Tan Yingy-ing²,3 Li Shuo*^,2 Yang Zhong-duo*^,3,4

(¹School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050)
(² Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnol-ogy, Peking University Shenzhen Graduate School, Shenzhen 518055)
(³ School of Life Science and Engineering, Lanzhou University of Technology, Lanzhou 730050)
(⁴ State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000)

Received:2009-11-27 Revised:2010-05-14 Published:2010-07-12
Contact: zhong-duo yang E-mail:yangzhongduo@126.com

Cite this article

LI Chun-Lei, WANG Yan-Chao, TAN Ying-Ying, LI Shuo, YANG Zhong-Duo. Stereospecific Synthesis of (2S,4S)/(2S,4R)-4-Fluoroglutamic Acids Base on Natural Chiral Source (4R)-Hydroxyproline[J]. Chin. J. Org. Chem., 2010, 30(12): 1931-1934.

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基于同一天然手性源(4R)-羟基脯氨酸的(2S,4S)/(2S,4R)-4-氟谷氨酸的立体专一性合成

Stereospecific Synthesis of (2S,4S)/(2S,4R)-4-Fluoroglutamic Acids Base on Natural Chiral Source (4R)-Hydroxyproline

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