Synthesis and biological activity of 3-methyl-4-  ethoxyl (diethylamino)carbonyl-1H-pyrazole derivatives

Abstract

In search of novel pyrazole derivatives with bioactivity, three series of 3-methyl-4-ethoxyl(diethylamino) carbonyl-1H-pyrazole derivatives were synthesized via α -oxoketene dithioacetals as starting material. The structures of all compounds prepared were confirmed by 1^H NMR, and elemental analyses, some were confirmed by IR and MS. Preliminary bioassays indicated that some compounds showed fungicidal activity against phoma asparagi.

Key words: PLANT PROTECTION, PLANT DISEASE, PYRAZOLE P, BENZENESULFONYL, SULFONYL GROUP, SYNTHESIS METHODS, BIOLOGICAL ACTIVITY

CLC Number:

O627

Cite this article

Zhao Weiguang;Li Zhengming;Yuan Pingwei;Yuan Dekai;Jia Qiang;Wang Wenyan;Wang Suhua. Synthesis and biological activity of 3-methyl-4- ethoxyl (diethylamino)carbonyl-1H-pyrazole derivatives[J]. Chin. J. Org. Chem., 2001, 21(8): 593-598.

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3-甲基-4-乙氧基(二乙氨基)羰基-1H-吡唑衍生物的合成及其生物活性