Chin. J. Org. Chem. ›› 2009, Vol. 29 ›› Issue (03): 450-453. Previous Articles     Next Articles

Reports

有机锌试剂制备Weinreb酰胺的研究

权 锋; 黄丹凤; 徐长明; 张正臣; 牛 腾;
冯惠娟; 徐雷云; 胡雨来*
  

  1. (西北师范大学化学化工学院 甘肃省高分子材料重点实验室 兰州 730070)
  • 收稿日期:2008-07-15 修回日期:2008-07-01 发布日期:2009-03-20
  • 通讯作者: 胡雨来

Preparation of Weinreb Amides Using Organozinc Iodides

Quan, Feng; Huang, Danfeng ; Xu, Changming; Zhang, Zhengchen ;
Niu, Teng ; Feng, Huijuan ; Xu, Leiyun ; Hu, Yulai*
  

  1. (Gansu Key Laboratory of Polymer Materials, College of Chemistry and Chemical Engineering,
    Northwest Normal University, Lanzhou 730070)
  • Received:2008-07-15 Revised:2008-07-01 Published:2009-03-20
  • Contact: Hu, Yulai

Organozinc halide with a Weinreb amide fuctional group was prepared directly from Weinreb amide iodide and zinc powder. The reaction of the organozinc halide with acyl chloride afforded a new series of Weinreb amides, which could be an effective method for the preparation of Weinreb amides.

Key words: acyl chloride, Weinreb amide, organozinc reagent