In the investigation of bioencapsulation technique, it was found that biological function can be incorporated into, and preserved within polymer matrices. After the introduction of sol-gel bioencapsulation a number of non-sol-gel polymers have been used to immobilize proteins. Various enzymes were trapped in such diverse polymers as epoxy-amine resins, polyvinyl plasticsm, polyurethane foams and silicon elastomers. Together with sol-gel encapsulates, these biocomposites represent a powerful approach for immobilizing biological materials for applications as biosensors and biocatalysts, and hold promise as bioactive, fouling-resistant polymers for enviromental, food and medical uses. Utilization of non-sel-gel polymer for bioencapsulation will be a strong alternative to the traditional entrapment methods of enzymes and proteins. hi this paper the most interesting non-sol-gel polymers, epoxy-amine resins and silicon elastomers are introduced in detail.

Key words: epoxy-amine resin;SILICON;PROTEIN;FIXATION;SENSORS, BIOLOGICAL ACTIVITY