A series of new N-Isononanoyl-N’-arylthiourea compounds were synthesized simply rapidly and high efficiently by serial reactions of triphosgene, isononanoic acid, potassium thiocyanate and aromatic amines, under solvent-free conditions, and confirmed by IR, 1H NMR and 13C NMR spectra. The crystal structure of compound 4g was determined by X-ray single crystal diffraction analysis. It belongs to monoclinic system with space group P2(1)/n, and a＝1.4365(4) nm, b＝0.7979(2) nm, c＝1.5521(4) nm, β＝94.814(4)°, V＝1.7726(8) nm3, Dx＝1.264 Mg•m－3, Z＝4, F(000)＝720, µ＝0.200 mm－1, R＝0.058, and wR＝0.231. The crystal structure of compound 4g shows that the compound was assembled to a layered structure by intermolecular hydrogen bond and the force between the moleculars of each layer. The preliminary biological activity tests show that some of the title compounds have some regulating activities for the growth of rape.

Key words: isononanoic acid, crystal structu, solvent-free, thiourea, triphosgene