Microbial reduction of macrocyclic ketones

Abstract

Microorganisms reduced cyclododecanone, cyclotridecanone, cyclotetradecanone, cyclopentadecanone, and cyclohexadecanone to the corresponding macrocyclic alcs. (e.g., cyclododecanol). No a,b-unsatd. compound was found. Microorganisms studied included Arthrobacter simplex, Mycobacterium smegmatis, Nocardia, Fusarium graminearum, F. solani, F. lateritium, Curvularia lunata, Beauveria, Streptomyces glaucescens, and Pseudomonas putida.

Key words: GAS CHROMATOGRAPHY, ARTHROBACTER, MACROCYCLIC COMPOUNDS, MICROBIAL TRANSFORMATION, KETONE

CLC Number:

O629

Cite this article

LI JINGLIAN;LI YOUHE;WANG DACHEN. Microbial reduction of macrocyclic ketones[J]. Chin. J. Org. Chem., 1986, 6(4): 309-312.

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