Synthesis and Biological Activity of N-Nitro-N-(2,4,6-trinitrophenyl) Urea

Chin. J. Org. Chem. ›› 2007, Vol. 27 ›› Issue (12): 1590-1593. Previous Articles Next Articles

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N-硝基-2,4,6-三硝基苯基脲的合成及生物活性研究

江洪*^,a,b，崔燕^a，方利^a，陈长水^a

(^a华中农业大学化学系武汉 430070)
(^b华中农业大学化学生物研究所武汉 430070)

收稿日期:2007-01-10 修回日期:2007-05-24 发布日期:2007-12-04
通讯作者: 江洪

Synthesis and Biological Activity of N-Nitro-N-(2,4,6-trinitrophenyl) Urea

JIANG Hong*^,a,b, CUI Yan^a, FANG Li^a, CHENG Chang-Shui^a

(^a Department of Chemistey, Huazhong Agricultural University, Wuhan 430070)
(^b Institute of Chemical Biology, Huazhong Agricultural University, Wuhan 430070)

Received:2007-01-10 Revised:2007-05-24 Published:2007-12-04
Contact: JIANG Hong

Abstract

N-Nitro-2,4,6-trinitroaniline reacted with bis(trichloromethyl) carbonate in toluene produced carbamoyl chloride. Treatment of the chloride, without any further purification, with substituted anilines gave thirteen novel N-nitro-N-(2,4,6-trinitrophenyl) urea derivatives. Their structures were confirmed by ¹H NMR, IR, MS spectra and elemental analysis. Preliminary biological tests show that some of these target compounds have good herbicidal activities against Echinochloa crusgalli beauv L at the concentration of 500 mg/L.

Key words: nitramide, bis(trichloromethyl) carbonate, herbicidal activity, N-nitro-N-(2,4,6-trinitrophenyl) urea

Cite this article

JIANG Hong*^,a,b, CUI Yan^a, FANG Li^a, CHENG Chang-Shui^a. Synthesis and Biological Activity of N-Nitro-N-(2,4,6-trinitrophenyl) Urea[J]. Chin. J. Org. Chem., 2007, 27(12): 1590-1593.

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N-硝基-2,4,6-三硝基苯基脲的合成及生物活性研究

Synthesis and Biological Activity of N-Nitro-N-(2,4,6-trinitrophenyl) Urea

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