Structural determination and spectral assignment of an alkaloid with a novel skeleton by selective long-range DEPT and 1D multiple relay COSY NMR techniques

Chin. J. Org. Chem. ›› 1998, Vol. 18 ›› Issue (3): 243-247. Previous Articles Next Articles

Original Articles

一维多重接力COSY和选择性远程DEPT核磁共振技术在新分子骨架生物碱结构测定和谱峰归属研究中的应用

缪振春;邓京振;赵守训;冯锐;杜泽涵

军事医学科学院毒物药物研究所;中国药科大学中草药化学研究室

发布日期:1998-06-25

Structural determination and spectral assignment of an alkaloid with a novel skeleton by selective long-range DEPT and 1D multiple relay COSY NMR techniques

MIU ZHENCHUN;DENG JINGZHEN;ZHAO SHUXUN;FENG RUI;DU ZEHAN

Published:1998-06-25

Abstract

A novel skeleton alkaloid, excentricine, was isolated from the roots of stephaniaexcentrica. The recent introduced selective long-range DEPT and 1D multiple relay COSY NMR techniques have been successfully used to identify and to connect spin systems separated by quaternary carbons and heterotoms and total assignment of 1H and 13C NMR spectra were achived. Its structure has been elucidated as 1.

Key words: NMR SPECTROMETRY, ISOQUINOLINE P, TETRAHYDROISOQUINOLINE ALKALOID, ALKALOID

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Cite this article

MIU ZHENCHUN;DENG JINGZHEN;ZHAO SHUXUN;FENG RUI;DU ZEHAN. Structural determination and spectral assignment of an alkaloid with a novel skeleton by selective long-range DEPT and 1D multiple relay COSY NMR techniques[J]. Chin. J. Org. Chem., 1998, 18(3): 243-247.

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一维多重接力COSY和选择性远程DEPT核磁共振技术在新分子骨架生物碱结构测定和谱峰归属研究中的应用

Structural determination and spectral assignment of an alkaloid with a novel skeleton by selective long-range DEPT and 1D multiple relay COSY NMR techniques

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