Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (08): 987-990. Previous Articles     Next Articles

Reports

微波促进下6-氨基-4-芳基-5-氰基-3-甲基-1-苯基吡啶[2,3-c]并吡唑的合成

朱松磊,屠树江*,李团结,章晓镜,纪顺俊*,张勇   

  1. (1徐州师范大学化学系 徐州 221116 )
    (2徐州医学院化学系 徐州 221002)
    (3苏州大学化学化工学院 苏州 215006)
  • 收稿日期:2004-10-29 修回日期:2005-02-01 发布日期:2005-07-30
  • 通讯作者: 屠树江, 纪顺俊

Synthesis of 6-Amino-4-aryl-5-cyano-3-methyl-1-phenylpyridino- [2,3-c]pyrazole under Microwave Irradiation

ZHU Song-Lei,TU Shu-Jiang*,LI Tuan-Jie,ZHANG Xiao-Jing
JI Shun-Jun*,ZHANG Yong   

  1. (1 Department of Chemistry, Xuzhou Normal University, Xuzhou 221116)
    (2 Department of Chemistry, Xuzhou Medical College, Xuzhou 221002)
    (3 College of Chemistry and Chemical Engineering, Suzhou University, Suzhou 215006)
  • Received:2004-10-29 Revised:2005-02-01 Published:2005-07-30
  • Contact: TU Shu-Jiang, JI Shun-Jun

A series of 6-amino-4-aryl-5-cyano-3-methyl-1-phenylpyridino[2,3-c]pyrazole derivatives were synthesized by the reaction of 5-amino-3-methyl-1-phenylpyrazole with arylidene derivatives of malononitrile under microwave irradiation. The reaction was completed in 4~8 min with 71%~90% yields. All the products were characterized by IR, 1H NMR spectra and elemental analysis. 3j was determined by the X-ray diffraction.

Key words: crystal structure, microwave, pyridino[2,3-c]pyrazole