Progress in the Studies on Antitumoral Natural Products from  Endophytic Fungi

Chin. J. Org. Chem. ›› 2008, Vol. 28 ›› Issue (10): 1697-1706. Previous Articles Next Articles

Review

植物内生真菌抗肿瘤活性成分研究进展

马养民* ; 冯成亮

(陕西科技大学化学与化工学院西安 710021)

收稿日期:2007-11-17 修回日期:2008-01-12 发布日期:2008-10-20
通讯作者: 马养民

Progress in the Studies on Antitumoral Natural Products from Endophytic Fungi

MA, Yang-Min* ; FENG, Cheng-Liang

(College of Chemistry and Chemical Engineering, Shaanxi University of Science and Technology, Xi’an 710021)

Received:2007-11-17 Revised:2008-01-12 Published:2008-10-20
Contact: MA, Yang-Min

Abstract

A number of antitumoral natural products have been isolated from endophytic fungi with diverse structures. Progress in various studies on antitumoral components is summarized, including the host plants of these endophytic fungi, the isolation and characterization of terpenoids, alkaloids, flavonoids, esters and steroids, and their inhibitory effects against tumor cells. In addition, the chemical ecology relationships between the endophytic fungi and their host plants are also briefly discussed.

Key words: metabolite, endophytic fungus, antitumor

Cite this article

MA, Yang-Min* ; FENG, Cheng-Liang. Progress in the Studies on Antitumoral Natural Products from Endophytic Fungi[J]. Chin. J. Org. Chem., 2008, 28(10): 1697-1706.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

[1]	Bozhen Wang, Jie Zhang, Chunhui Nian, Mingming Jin, Miaomiao Kong, Wulan Li, Wenfei He, Jianzhang Wu. Synthesis and Antitumor Activity of 3,4-Dichlorophenyl Amides [J]. Chinese Journal of Organic Chemistry, 2024, 44(1): 232-241.
[2]	Panxing Pang, Rong Ning, Chuang Zhu, Wenjie Huang, Xianli Ma, Caina Jiang, Fangyao Li, Xiaoqun Zhou. Synthesis and in Vitro Antitumor Activity of Matrine Semicarbazide Derivatives [J]. Chinese Journal of Organic Chemistry, 2023, 43(6): 2126-2135.
[3]	Kanghui Duan, Junlong Tang, Wanqing Wu. Recent Advances in the Synthesis of Fused Heterocyclic Compounds and Their Antitumor Activities [J]. Chinese Journal of Organic Chemistry, 2023, 43(3): 826-854.
[4]	Chujie Liao, Hongyao Ruan, Junfeng Jiang, Lun Luo, Yanggen Hu. Synthesis and Activity Evaluation of 3-Aryl-2-imino-benzo[e][1,3]-oxazin-4-ol Derivatives [J]. Chinese Journal of Organic Chemistry, 2023, 43(2): 763-770.
[5]	Bingwen Zhang, Yuqi Lin, Yanqing Xue, Jing Wang, Wenchao Yang, Xiaofeng Wang, Wen Liu. Study on Secondary Metabolites from Fusarium graminearum [J]. Chinese Journal of Organic Chemistry, 2023, 43(11): 4003-4007.
[6]	Weiqin Liu, Lihui Shao, Chengpeng Li, Yayu Zou, Haitao Long, Yan Li, Qiangsheng Ge, Zhenchao Wang, Guiping Ouyang. Synthesis and Antitumor Activity of 3-Hydrazone Quinazolinone Derivatives [J]. Chinese Journal of Organic Chemistry, 2023, 43(1): 214-222.
[7]	Guangping Liang, Wei Wang, Xuxiu Zhu, Guangyan Liang, Jun Yang, Daoping Wang. Synthesis and in Vitro Anti-tumor Activity of Novel Spliced Compounds of Zidovudine and 4-Anilinoquinazolines [J]. Chinese Journal of Organic Chemistry, 2022, 42(9): 2793-2805.
[8]	Dongyan Hu, Guangtian Han, Xi'an Li, Huazhong Ren, Lirong Yue, Li Guo, Jiafu Feng. Synthesis and Evaluation in vitro of Novel Harmine Derivatives as Anticancer Activity Agents [J]. Chinese Journal of Organic Chemistry, 2022, 42(6): 1863-1871.
[9]	Lu Xue, Lihua Zhang, Chengyu Zhang, Xin Zhao, Weifan Dang, Zhaoxin Wang, Chunhua Wang, Tongchuan Suo, Xiaohui Yan. Discovery of Tiancimycin Congeners from Streptomyces sp. CB03234-S [J]. Chinese Journal of Organic Chemistry, 2022, 42(4): 1241-1247.
[10]	Siyu Zhu, Xinyu Huo, Qin Ma, Wei Chen, Jie Zhang, Liang Guo. Design, Synthesis, and Antitumor Activity of β-Carboline-Benzimidazole Hybrids [J]. Chinese Journal of Organic Chemistry, 2022, 42(4): 1129-1135.
[11]	Jing-Yu Yang, Min-Min Tang, Li Chen, Xin-Yi Lai, Xin Zhuo, Xue-Ming Zhou, Guang-Ying Chen. Study on the Secondary Metabolites of Endophytic Penicillium sclerotiorum HLL113 [J]. Chinese Journal of Organic Chemistry, 2022, 42(3): 896-900.
[12]	Honglin Dai, Xiaojie Si, Lingling Chi, Hao Wang, Chao Gao, Zhengjie Wang, Limin Liu, Jiajie Ma, Fuqiang Yu, Hongmin Liu, Yu Ke, Qiurong Zhang. Synthesis and Antitumor Activity Evaluation of 2,4,6-Trisubstituted Quinazoline Derivatives Containing Thiazole Structure [J]. Chinese Journal of Organic Chemistry, 2022, 42(11): 3853-3862.
[13]	Zhengjie Wang, Honglin Dai, Xiaojie Si, Chao Gao, Limin Liu, Luye Zhang, Yang Zhang, Yadan Song, Peirong Zhao, Jiaxin Zheng, Yu Ke, Hongmin Liu, Qiurong Zhang. Synthesis and Antitumor Activity of 2,4,6-Trisubstituted Novel Quinazoline Derivatives Containing Trifluoromethyl [J]. Chinese Journal of Organic Chemistry, 2022, 42(1): 249-256.
[14]	Lijun Yin, Chaoqun Li, Xiaoxia Wu, Guangsen Xu, Zhiying Li, Yuemao Shen. Synthesis of (E)-N-(4-Styrene) Acrylamides for DNA Topoisomerase IIα Inhibitors and Antitumor Agents [J]. Chinese Journal of Organic Chemistry, 2022, 42(1): 293-301.
[15]	Jiaoli Ma, Penghu Guo, Jing Li, Xincheng Liao, Huicheng Cheng. Synthesis and Antitumor Activity of Amide Derivatives Containing 1,3,4-Thiadiazole and Pyrazole Moieties [J]. Chinese Journal of Organic Chemistry, 2021, 41(8): 3214-3222.

植物内生真菌抗肿瘤活性成分研究进展

Progress in the Studies on Antitumoral Natural Products from Endophytic Fungi

PDF

Knowledge

Cited

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments