Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (11): 1934-1938. Previous Articles     Next Articles

Notes

低价钛试剂促进下2-(2-硝基苯基)咪唑与席夫碱的反应

窦国兰1,仲晓星1,王德明*1,史达清2   

  1. (1中国矿业大学安全工程学院 徐州 221116)
    (2苏州大学材料与化学化工学部 苏州 215123)
  • 收稿日期:2011-04-30 修回日期:2011-06-22 发布日期:2011-07-14
  • 通讯作者: 窦国兰 E-mail:wdmcumt@163.com
  • 基金资助:

    中央高校基本科研业务费专项资金

A Novel Reaction of 2-(2-Nitrophenyl)imidazole with Schiff Base Promoted by Low-Valent Titanium Reagent

Dou Guolan1 Zhong Xiaoxing1 Wang Dem-ing*1 Shi Daqing2   

  1. (1 School of Safety Engineering, China University of Mining and Technology, Xuzhou 221116)
    (2 Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemis-try, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123)
  • Received:2011-04-30 Revised:2011-06-22 Published:2011-07-14
  • Contact: De-Ming Wang E-mail:wdmcumt@163.com

The intermolecular reductive cyclodimerizations of 2-(2-nitrophenyl)imidazoles with Schiff bases induced by low-valent titanium reagent in anhydrous THF were studied. The cleavage of C=N bond is superior to coupling of 2-(2-nitrophenyl)imidazoles with Schiff base. Thus, 5,6-dihydroimidazo[1,2-c]- quinazolines were obtained in good yields.

Key words: low-valent titanium, 2-(2-nitrophenyl)imidazole, Schiff base