Chin. J. Org. Chem. ›› 2013, Vol. 33 ›› Issue (12): 2443-2459.DOI: 10.6023/cjoc201308023 Previous Articles     Next Articles

Reviews

白藜芦醇低聚物的化学选择性合成

李文玲, 吕腾, 杨玉华, 杨亚东   

  1. 兰州交通大学化学与生物工程学院 兰州 730070
  • 收稿日期:2013-08-19 修回日期:2013-09-27 发布日期:2013-09-30
  • 通讯作者: 李文玲 E-mail:liwl@mail.lzjtu.cn
  • 基金资助:

    国家自然科学基金(No. 21062010)、兰州交通大学青蓝人才工程基金(No. QL-08-06A)资助项目.

Chemoselectively Synthesis of Resveratrol Oligomers

Li Wenling, Lü Teng, Yang Yuhua, Yang Yadong   

  1. School of Chemical and Biological Engineering, Lanzhou Jiaotong University, Lanzhou 730070
  • Received:2013-08-19 Revised:2013-09-27 Published:2013-09-30
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21062010), the "Qing Lan" Talent Engineering Funds of Lanzhou Jiaotong University (No. QL-08-06A).

Resveratrol oligomers are a class of plant polyphenols which are formed in nature by oxidative oligomerization of resveratrol catalyzed by enzymes and have received considerable attention of synthetic chemists on account of their structural complexity and diverse biological activities. The biomimetic synthetic strategy based on the oxidative coupling reaction has been extensively studied over the past thirty years, but the lacks of regio-or stereo-selectivity impose restrictions on its universal application. Recently, The synthetic efforts on the diverse skeletons of these oligomers through novel and effective cascade reactions has been a hot research topic and have achieved dramatic success. And they were mostly focused on the synthesis of racemates and the asymmetric synthesis research on these oligomers has just started. In this paper, the progress in the chemical syntheses of resveratrol oligomers in recent seven years is reviewed in detail and the future synthetic trend of oligostilbenes is also prospected.

Key words: resveratrol, oligomerization, chemoselectivity, total synthesis