Chin. J. Org. Chem. ›› 2014, Vol. 34 ›› Issue (10): 2015-2020.DOI: 10.6023/cjoc201406018 Previous Articles     Next Articles

Articles

五个天然异戊烯基黄酮的首次全合成研究

冯尧, 杨金会, 马晓琴, 陈兵兵, 谢一民   

  1. 宁夏大学天然气转化国家重点实验室培育基地 银川 750021
  • 收稿日期:2014-06-14 修回日期:2014-08-08 发布日期:2014-08-26
  • 通讯作者: 杨金会 E-mail:yang_jh@nxu.edu.cn
  • 基金资助:

    国家自然科学基金(Nos. 21162021,21362025)、教育部新世纪优秀人才支持计划(No. NCET-09-0860)资助项目.

First Total Synthesis of Five Natural Prenylated Flavonoids

Feng Yao, Yang Jinhui, Ma Xiaoqin, Chen Bingbing, Xie Yimin   

  1. State Key Laboratory Cultivation Base of Natural Gas Conversion, Ningxia University, Yinchuan 750021
  • Received:2014-06-14 Revised:2014-08-08 Published:2014-08-26
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21162021, 21362025) and the Program for New Century Excellent Talents in University (No. NCET-09-0860).

A simple and efficient approach for synthesis flavonoids with 2,3-dihydroxy-3-methylbutyl moiety, by which seven natural prenylated flavonoids, brosimacutin A-B, brosimacutin D, brosimacutin E, brosimacutin H and brosimacutin M have been synthesized in racemic form. All structures of new compounds were confirmed by NMR and HRMS.

Key words: prenylated flavonoids, chalcone, dihydrochalcones, total synthetic, brosimacutin