Hydrogenation of Alkynes to cis-Alkenes with Hydrazine in Air

doi:10.6023/cjoc201701040

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (6): 1407-1411.DOI: 10.6023/cjoc201701040 Previous Articles Next Articles

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水合肼选择性还原炔烃至顺式烯烃研究

王金涛, 熊就凯, 李娟娟, 王佳利, 王克让, 李小六

河北大学化学与环境科学学院药物化学与分子诊断教育部重点实验室河北省化学生物学重点实验室保定 071002

收稿日期:2017-01-20 修回日期:2017-02-19 发布日期:2017-02-27
通讯作者: 王克让,李小六 E-mail:kerangwang@hbu.edu.cn;lixl@hbu.edu.cn
基金资助:
国家自然科学基金（Nos.21372059，21572044）和河北省自然科学基金（Nos.B2016201254，2016201031）资助项目.

Hydrogenation of Alkynes to cis-Alkenes with Hydrazine in Air

Wang Jintao, Xiong Jiukai, Li Juanjuan, Wang Jiali, Wang Kerang, Li Xiaoliu

Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of Ministry of Education, Key Laboratory of ChemicalBiology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002

Received:2017-01-20 Revised:2017-02-19 Published:2017-02-27
Contact: 10.6023/cjoc201701040 E-mail:kerangwang@hbu.edu.cn;lixl@hbu.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (Nos. 21372059, 21572044), and the Natural Science Foundation of Hebei Province (Nos. B2016201254, 2016201031).

1. Hydrogenation of Alkynes to cis-Alkenes with Hydrazine in Air.PDF(436KB)

Abstract

Transfer hydrogenation is a mild and effective way in reduction reaction. In this paper, a simple approach of selectively hydrogenation of alkynes to cis-alkenes with NH₂NH₂·H₂O as a transfer hydrogenation agent in the presence of air without any catalysts or metals was developed. Furthermore, the configuration of cis-alkene was confirmed by the 2D NOESY spectrum.

Key words: transfer hydrogenation, hydrazine, alkynes, alkenes, diazene

Cite this article

Wang Jintao, Xiong Jiukai, Li Juanjuan, Wang Jiali, Wang Kerang, Li Xiaoliu. Hydrogenation of Alkynes to cis-Alkenes with Hydrazine in Air[J]. Chin. J. Org. Chem., 2017, 37(6): 1407-1411.

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水合肼选择性还原炔烃至顺式烯烃研究

Hydrogenation of Alkynes to cis-Alkenes with Hydrazine in Air

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