Study of the Friedel-Crafts Reaction of Cyanuric Chloride with Low-Boiling Aromatic Ring

doi:10.6023/cjoc201704027

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (10): 2697-2704.DOI: 10.6023/cjoc201704027 Previous Articles Next Articles

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三聚氯氰与低沸点芳香环的Friedel-Crafts封管反应研究

邹浩^a, 王雪丁^a, 杨维清^a, 张园园^a, 陈华^b, 王玉良^b, 马梦林^a, 杜泉^a

a 西华大学理学院四川省先进计算重点实验室成都 610039;
b 四川大学化学学院教育部绿色化学重点实验室成都 610064

收稿日期:2017-04-17 修回日期:2017-05-22 发布日期:2017-06-16
通讯作者: 马梦林 E-mail:mmlchem@163.com
基金资助:
四川省自然科学基金重点（No.12ZB128）和西华大学重点（No.Z1123328）资助项目.

Study of the Friedel-Crafts Reaction of Cyanuric Chloride with Low-Boiling Aromatic Ring

Zou Hao^a, Wang Xueding^a, Yang Weiqing^a, Zhang Yuanyuan^a, Chen Hua^b, Wang Yuliang^b, Ma Menglin^a, Du Quan^a

a Key Laboratory of Advanced Scientific Computation of Sichuan Province, School of Science, Xihua University, Chengdu 610039;
b Key Laboratory of Green Chemistry and Technology of Ministry of Education, Faculty of Chemistry, Sichuan University, Chengdu 610064

Received:2017-04-17 Revised:2017-05-22 Published:2017-06-16
Contact: 10.6023/cjoc201704027 E-mail:mmlchem@163.com
Supported by:
Project supported by the Scientific Research Foundation of the Education Department of Sichuan Province (No.12ZB128) and the Key Research Fund Program of Xihua University (No.Z1123328).

1. Study of the Friedel-Crafts Reaction of Cyanuric Chloride with Low-Boiling Aromatic Ring.PDF(1130KB)

Abstract

The cyanuric chloride and benzene Friedel-Crafts arylation using Lewis acid catalyst in high pressure autoclave was studied in this manuscript. The aim compounds 2,4-dichloro-6-phenyl-1,3,5-triazine and 2,4,6-triphenyl-1,3,5-triazine could be got with high selectivity and yields by varying reaction temperature, substrate and catalyst amount, which application was expecting and promising. The transition state was obtained by quantum calculation density functional theory (DFT) method using Gaussian software, and the experimental results and mechanism of this reaction were discussed from the point of dynamics and thermo-dynamics.

Key words: cyanuric chloride, aromatic ring, friedel-crafts arylation reaction, autoclave

Cite this article

Zou Hao, Wang Xueding, Yang Weiqing, Zhang Yuanyuan, Chen Hua, Wang Yuliang, Ma Menglin, Du Quan. Study of the Friedel-Crafts Reaction of Cyanuric Chloride with Low-Boiling Aromatic Ring[J]. Chin. J. Org. Chem., 2017, 37(10): 2697-2704.

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三聚氯氰与低沸点芳香环的Friedel-Crafts封管反应研究

Study of the Friedel-Crafts Reaction of Cyanuric Chloride with Low-Boiling Aromatic Ring

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