Synthesis of Iminopyrrolone Compounds

doi:10.6023/cjoc201705004

Chin. J. Org. Chem. ›› 2017, Vol. 37 ›› Issue (10): 2690-2696.DOI: 10.6023/cjoc201705004 Previous Articles Next Articles

ARTICLE

亚胺基吡咯酮类化合物的合成

赵宇澄, 肖强, 王保取, 林军, 严胜骄

云南大学化学科学与工程学院教育部自然资源药物化学重点实验室昆明 650091

收稿日期:2017-05-02 修回日期:2017-06-16 发布日期:2017-06-23
通讯作者: 林军, 严胜骄 E-mail:linjun@ynu.edu.cn;yansj@ynu.edu.cn
基金资助:
国家自然科学基金（Nos.21362042，21662042，U1202221，21262042）、云南省自然科学基金（No.2017FA003）、云南省后备人才（2012HB001）、云南大学东陆学者，云南大学青年英才计划资助项目（No.XT412003）.

Synthesis of Iminopyrrolone Compounds

Zhao Yucheng, Xiao Qiang, Wang Baoqu, Lin Jun, Yan Shengjiao

Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091

Received:2017-05-02 Revised:2017-06-16 Published:2017-06-23
Contact: 10.6023/cjoc201705004 E-mail:linjun@ynu.edu.cn;yansj@ynu.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (Nos.21362042,21662042,U1202221,21262042),the Natural Science Foundation of Yunnan Province (No.2017FA003),the Talent Found in Yunnan Province (No.2012HB001),the Donglu Scholar of Yunnan University and the Excellent Young Talents in Yunnan University (No.XT412003).

1. Synthesis of Iminopyrrolone Compounds.PDF(3959KB)

Abstract

The method was constructed for synthesis of pyrrolone compounds, which was based on the reaction of 1,1-endiamine (1) with maleic anhydride (2) in 1,4-dioxane at reflux in alkali condition (Et₃N). As a result, a series of iminopyrrolone compounds have been synthesized by this reaction. This protocol possesses some advantages including readily available starting materials, simple operation and concise synthetic route and so on.

Key words: iminopyrrolone, nitro-enamine, synthesis

Cite this article

Zhao Yucheng, Xiao Qiang, Wang Baoqu, Lin Jun, Yan Shengjiao. Synthesis of Iminopyrrolone Compounds[J]. Chin. J. Org. Chem., 2017, 37(10): 2690-2696.

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亚胺基吡咯酮类化合物的合成

Synthesis of Iminopyrrolone Compounds

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