Research on Reduction of α,α,α-Tribromomethyl Ketones via Thiophenol

doi:10.6023/cjoc201810003

Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (3): 727-733.DOI: 10.6023/cjoc201810003 Previous Articles Next Articles

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苯硫酚还原α,α,α-三溴甲基酮类化合物的研究

杨莹, 哈斯木江·巴拉提, 阿布都热西提·阿布力克木

新疆师范大学化学系乌鲁木齐 830054

收稿日期:2018-10-05 修回日期:2018-11-07 发布日期:2018-11-26
通讯作者: 阿布都热西提·阿布力克木 E-mail:aarexit@xjnu.edu.cn
基金资助:
国家自然科学基金（No.21662035）资助项目.

Research on Reduction of α,α,α-Tribromomethyl Ketones via Thiophenol

Yang Ying, Balati Hasimujiang, Abulikemu Abudu Rexit

Department of Chemistry, Xinjiang Normal University, Urumqi 830054

Received:2018-10-05 Revised:2018-11-07 Published:2018-11-26
Contact: 10.6023/cjoc201810003 E-mail:aarexit@xjnu.edu.cn
Supported by:
Project supported by the National Natural Science Foundation of China (No. 21662035).

1. Research on Reduction of α,α,α-Tribromomethyl Ketones via Thiophenol.PDF(4680KB)

Abstract

α,α-Dibromomethyl ketones were synthesized with high yields through a thiophenol-promoted reduction of α,α,α-tribromomethyl ketones under mild conditions within one hour. A further mechanistic study showed that the reaction proceeded via a radical process. This is an example that uses thiophenol as the radical stimulator in the reduction of multi-halogenated compounds.

Key words: thiophenol, α,α-dibromomethyl ketones, green synthesis, reduction

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Yang Ying, Balati Hasimujiang, Abulikemu Abudu Rexit. Research on Reduction of α,α,α-Tribromomethyl Ketones via Thiophenol[J]. Chin. J. Org. Chem., 2019, 39(3): 727-733.

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苯硫酚还原α,α,α-三溴甲基酮类化合物的研究

Research on Reduction of α,α,α-Tribromomethyl Ketones via Thiophenol

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