Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (11): 4459-4466.DOI: 10.6023/cjoc202106035 Previous Articles Next Articles
ARTICLES
苟铨a,*(), 谭秋健a, 陈乾琼a, 谭建红a, 王凯民c, 谢剑锋b,*(
)
收稿日期:
2021-06-21
修回日期:
2021-07-17
发布日期:
2021-07-26
通讯作者:
苟铨, 谢剑锋
基金资助:
Quan Goua(), Qiujian Tana, Qianqiong Chena, Jianhong Tana, Kaimin Wangc, Jianfeng Xieb(
)
Received:
2021-06-21
Revised:
2021-07-17
Published:
2021-07-26
Contact:
Quan Gou, Jianfeng Xie
Supported by:
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Quan Gou, Qiujian Tan, Qianqiong Chen, Jianhong Tan, Kaimin Wang, Jianfeng Xie. Copper-Catalyzed Regioselective C(sp3)—H Sulfonimidization of Aliphatic Cyclic Tertiary Amines[J]. Chinese Journal of Organic Chemistry, 2021, 41(11): 4459-4466.
Entry | Cat. Cu | Solvent | Additive | Yieldb/% |
---|---|---|---|---|
1 | CuBr | PhCF3 | — | 60 |
2 | CuBr | DMF | — | 40 |
3 | CuBr | Mesitylene | — | 87 |
4 | CuBr | dioxane | — | 42 |
5 | — | Mesitylene | — | 0 |
6 | CuI | Mesitylene | — | 0 |
7 | Cu2O | Mesitylene | — | Trace |
8 | CuCl | Mesitylene | — | 92 |
9 | Cu(OAc)2 | Mesitylene | — | 20 |
10 | CuCl2 | Mesitylene | — | 83 |
11c | CuCl | Mesitylene | — | 0 |
12 | CuCl | Mesitylene | Na2CO3 | 60 |
13 | CuCl | Mesitylene | K2CO3 | 0 |
14d | CuCl | Mesitylene | — | 80 |
Entry | Cat. Cu | Solvent | Additive | Yieldb/% |
---|---|---|---|---|
1 | CuBr | PhCF3 | — | 60 |
2 | CuBr | DMF | — | 40 |
3 | CuBr | Mesitylene | — | 87 |
4 | CuBr | dioxane | — | 42 |
5 | — | Mesitylene | — | 0 |
6 | CuI | Mesitylene | — | 0 |
7 | Cu2O | Mesitylene | — | Trace |
8 | CuCl | Mesitylene | — | 92 |
9 | Cu(OAc)2 | Mesitylene | — | 20 |
10 | CuCl2 | Mesitylene | — | 83 |
11c | CuCl | Mesitylene | — | 0 |
12 | CuCl | Mesitylene | Na2CO3 | 60 |
13 | CuCl | Mesitylene | K2CO3 | 0 |
14d | CuCl | Mesitylene | — | 80 |
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