Chinese Journal of Organic Chemistry 2025, 45(10)

- About the Cover:
  
  A novel electrochemical synthetic system for β-keto sulfonyl fluorides has been successfully developed by Feng, He, Li, Li, and Huang on page 3885. β-Keto sul-fonyl fluorides were synthesized using vinyl acetate and sulfuryl chlorofluoride under electrochemical conditions. The electroreductive strategy requires neither sacrificial electrodes nor metal catalysts, thus featuring mild conditions and a wide substrate scope, which enables the synthesis of various β-keto sulfonyl fluorides from sim-ple ketone feedstocks. Moreover, this transformation can be performed in a continuous flow reactor
- About the Cover:
  
  A direct nitration of tertiary enamide with tert-butyl nitrite (tBuONO) under metal-free conditions is disclosed by Liu, Xu, Wang, Liu, Chen, and Sun on page 3903. A wide array of cyclic and acyclic enamides was nitrated with commercially available nonmetallic reagents, which produced diverse valuable β-acylamino nitroalkenes in excellent yields. Furthermore, this protocol is operationally simple and exhibits broad substrate scope and good functional group compatibility.
- About the Cover:
  
  The recent progress in radical arylation reaction with diaryliodonium salts is reviewed by Zhu, Jiao, Wei, Chen, and Mo on page 3672. Radical arylations induced by visible light or without photocatalysis were used to the construction of carbon-carbon and carbon-hetero- atom bonds, and successfully applied in the synthesis of arylated bioactive compounds.
- About the Cover:
  
  Atropisomeric phosphines are crucial to asymmetric catalysis yet challenging to synthesize. An N-hetero-cyclic carbene catalyzed reaction between dialdehydes and arylboronic acids is reported by Huang, Lin, Li, Zhang, Wang, Gao, Gong, Li, and Liu on page 3847. Mechanistic studies have revealed that the reaction initially undergoes a desymmetrization process, followed by a kinetic resolution pathway, affording a series of axially chiral phosphorus compounds with high enantio- selectivity.
2025, 45(10)

25 October 2025
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REVIEWS ARTICLES HIGHLIGHTS

REVIEWS

Research Progress on Visible Light-Induced Oxidative Difun-ctionalization of Olefins with Molecular Oxygen

Leilei Wang, Ya'nan Hou, Hongyu Ding, Juanjuan Wu, Zuli Wang, Wei Wei, Dong Yi

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3495-3516 DOI: 10.6023/cjoc202506019

Abstract( 186) HTML( 16) PDF(1026KB)( 150 )

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Iron-Photocatalytic Decarboxylative Functionalization Based on Ligand-to-Metal Charge Transfer

Chenchen Zhang, Qingjie Ding, Qiyan Lv, Chunhua Ma, Yuqin Jiang, Bing Yu

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3517-3533 DOI: 10.6023/cjoc202505025

Abstract( 159) HTML( 10) PDF(1079KB)( 118 )

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Application Progress of Langlois Reagent in Electrochemical Trifluoromethylation Reactions

Weibao He, Rongnan Yi, Zi Yang, Zhilin Wu, He

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3534-3545 DOI: 10.6023/cjoc202506034

Abstract( 125) HTML( 7) PDF(661KB)( 95 )

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Research Progress on Photocatalytic Synthesis of Eight Nitrogen-Containing Heterocycles

Yiqi Liu, Wenjie Chen, Zeyan Zhao, Suqi Wang, Shengsong Tang, Wei-Min He, Junmei Peng

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3546-3586 DOI: 10.6023/cjoc202505018

Abstract( 148) HTML( 8) PDF(1557KB)( 136 )

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Recent Progress in the Dehydroxylative Functionalizations of Alcohols

Yanyan Jiao, Feige Wang, Jian Xiao, Xiaode An

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3587-3612 DOI: 10.6023/cjoc202506010

Abstract( 148) HTML( 10) PDF(1115KB)( 154 )

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Isosteviol-Type Organocatalysts in Asymmetric Catalysis over the Past Decade

Yuxia Liu, Congcong Li, Zhaoyang Fan, Qi Liu, Xinyu Dai

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3613-3623 DOI: 10.6023/cjoc202505008

Abstract( 122) HTML( 8) PDF(833KB)( 60 )

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Research Progress and Application of Chiral Macrocycles in Supramolecular Catalysis

Shenglan Huang, Liupan Yang, Lili Wang, Huan Yao

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3624-3643 DOI: 10.6023/cjoc202502040

Abstract( 209) HTML( 10) PDF(6446KB)( 186 )

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Recent Advances in the Radical Reactions of Dihydroquinazolinone Derivatives

Zijie Li, Zheng Hao, Shengyuan Yang, Wenchao Yang, Tao Jin

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3644-3654 DOI: 10.6023/cjoc202501014

Abstract( 262) HTML( 7) PDF(857KB)( 130 )

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Recent Progress on the Difunctionalization Reaction of 1,3-Enynes

Lianglong Sun, Kai Sun

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3655-3671 DOI: 10.6023/cjoc202502004

Abstract( 237) HTML( 10) PDF(905KB)( 145 )

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Recent Progress in Radical Arylation Reaction Involving Diaryliodonium Salts

Yu'nan Zhu, Weikang Jiao, Xuebai Wei, Chunhua Chen, Dongliang Mo

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3672-3690 DOI: 10.6023/cjoc202412026

Abstract( 226) HTML( 7) PDF(1026KB)( 206 )

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Research Progress on the Synthesis of 2-Oxindoles via Radical Cascade Cyclization of N-Arylacrylamide

Zhilin Wu, Wei Luo, Rou Ding, Cui Xin, Congyang Wang, Wei-Min He

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3691-3700 DOI: 10.6023/cjoc202501016

Abstract( 257) HTML( 7) PDF(596KB)( 212 )

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Recent Advances in Electrochemical Formation of C—S Bond and Construction of Organosulfur Compounds

Shiyi Zhuang, Xiaoqin You, Weiwei Jin

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3701-3718 DOI: 10.6023/cjoc202411019

Abstract( 229) HTML( 4) PDF(992KB)( 185 )

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Research Progress in the Synthesis of Phosphorothioates Driven by Photo/Electrochemistry

Guoju Guo, Qilong Wu, Yuzhen Dong, Jie Zhang, Yongjia Shi, Qing Liu, Daoshan Yang

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3719-3740 DOI: 10.6023/cjoc202410018

Abstract( 255) HTML( 3) PDF(921KB)( 440 )

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Cyclization of N-(2-Ethynylphenyl)acrylamides for the Synthesis of Heteropolycyclic Compounds

Daoqing Dong, Yimeng Wang, Gengning Zhu, Yanli Wang, Shuguang Yu, Juan Liu, Jianxin Feng, Xinming Xu, Shiqiang Yan, Zuli Wang

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3741-3754 DOI: 10.6023/cjoc202409034

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Recent Progress in Gold-Catalyzed Intramolecular Cyclization of Alkynes and Its Applications

Xu Zhang, Peisen Zou, Xiaoqing Liu, Hongyan Bi, Dongliang Mo

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3755-3776 DOI: 10.6023/cjoc202407034

Abstract( 507) HTML( 5) PDF(1324KB)( 770 )

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ARTICLES

Synthesis of 2,4,6-Trisubstituted Pyridines via Cobalt-Catalyzed Homocoupling of α,β-Unsaturated Ketone Oxime Esters

Zhanxiang Liu, Chao Hong, Siyuan Li, Shengru Huang, Ningxia Zhang, Ruokun Feng, Yuhong Zhang

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3777-3785 DOI: 10.6023/cjoc202506037

Abstract( 105) HTML( 5) PDF(2428KB)( 71 )

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Synthesis of Selenylated Maleimides and Alkenes via Bromide Catalysis

Zhouting Zeng, Huaixin Wei, Wei-Min He, Mingming Yu, Zu-Li Wang, Jinhui Cai

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3786-3796 DOI: 10.6023/cjoc202506004

Abstract( 122) HTML( 3) PDF(613KB)( 69 )

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Direct 1,3-Azidoheteroarylation of [1.1.1]Propellane with Cyclic Aldimines and Azidotrimethylsilane (TMSN₃) under Mild Conditions

Yuxin Wang, Jingyi Zhang, Yibo Wang, Binye Cao, Xinchang Wang, Jiabin Shen, Yihan Gao, Wanmei Li

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3797-3806 DOI: 10.6023/cjoc202504022

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Electrochemical Multicomponent Cascade Synthesis of 4-Selenylacylpyrazoles

Shuyang Guo, Yumeng He, Xiaomin Cheng, Yuxing Gao, Yuqi Zhang, Haojie Ma, Wei-Min He

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3807-3815 DOI: 10.6023/cjoc202503018

Abstract( 117) HTML( 3) PDF(684KB)( 54 )

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Synthesis of 9-Cyanoanthracene Derivatives by Tandem Reaction of Aryne with ortho-Arylformylphenylacetonitrile

Shuangjun Li, Yi Gong, Fang Zhang, Guangfen Du, Lin He

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3816-3823 DOI: 10.6023/cjoc202503005

Abstract( 115) HTML( 4) PDF(663KB)( 100 )

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One-Pot Transition-Metal-Free Synthesis of Carboline Derivatives via Dual C—N Bond Formation

Guiling Xie, Sudhakar Reddy Mopuri, Jie Li, Yuanyong Yang, Tie-Gen Chen

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3824-3837 DOI: 10.6023/cjoc202505007

Abstract( 183) HTML( 7) PDF(810KB)( 128 )

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Synthesis of Heteroatom-Bridged Six-Membered Cyclic Diaryliodonium Salts

Shanyan Jiao, Khan Hamza, Limin Wang, Jianwei Han

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3838-3846 DOI: 10.6023/cjoc202502029

Abstract( 102) HTML( 3) PDF(554KB)( 59 )

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N-Heterocyclic Carbene Catalyzed Esterification of Dicarbaldehydes with Arylboronic Acid for Axially Chiral Phosphorus Compounds

Xuehui Huang, Yanru Lin, Zhaodi Li, Yue Zhang, Xin Wang, Gao Yuanyuan, Xiaojie Gong, Fei Li, Lantao Liu

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3847-3855 DOI: 10.6023/cjoc202504014

Abstract( 108) HTML( 5) PDF(624KB)( 50 )

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Metal-Free Cascade Isocyanide Phosphorylation/Cyclization to Synthesize 2-Phosphinoylindoles

Ruifeng Cao, Lin Xiao, Tianyu Long, Jiadong Gu, Yanghua Li, Han-Han Kong, Qing-Qing Yang, Nianyu Huang, Long Wang

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3856-3865 DOI: 10.6023/cjoc202503002

Abstract( 141) HTML( 3) PDF(641KB)( 86 )

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Electron Paramagnetic Resonance (EPR) Studies of Photocatalytic Halogen Atom Transfer Intermediates Involving Organic Amines and Its Applications

Weijun Jin, Ke Ren, Guanglu Zhang, Min Jiang

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3866-3872 DOI: 10.6023/cjoc202502030

Abstract( 157) HTML( 2) PDF(1787KB)( 69 )

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Study on Synthesis of Glycine by Electrooxidation of Ethanolamine

Ying Li, Shuozhen Hu, Wei Fang, Xing Xiao, Xinsheng Zhang

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3873-3884 DOI: 10.6023/cjoc202502009

Abstract( 152) HTML( 3) PDF(1943KB)( 164 )

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Electrochemical Synthesis of β-Keto Sulfonyl Fluorides via Radical Fluorosulfonylation of Vinyl Acetates

Qingyuan Feng, Tianyu He, Shuohai Li, Mei Li, Shenlin Huang

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3885-3891 DOI: 10.6023/cjoc202412021

Abstract( 122) HTML( 1) PDF(580KB)( 149 )

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Three-Component Reaction of Isothiocyanates, Amines, and Sulfonium Salts Leading to S-Alkyl Isothioureas

Zheng Wang, Min Yue, Zongcheng Wang

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3892-3902 DOI: 10.6023/cjoc202412015

Abstract( 58) HTML( 0) PDF(593KB)( 22 )

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Direct Nitration of Enamide to β-Acylamino Nitroalkenes under Metal-Free Conditions

Fei Liu, Xinming Xu, Xin Wang, Chunyang Liu, Xuebo Chen, Kai Sun

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3903-3911 DOI: 10.6023/cjoc202412011

Abstract( 186) HTML( 0) PDF(696KB)( 125 )

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Visible-Light-Promoted Multi-Component Reaction of α-Diazoesters to Construct Alkyl Phosphorodithioates

Yaping Feng, Jian Huang, Yingjie Wang, Jian Sun, Guangming Nan, Wei Wei

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3912-3922 DOI: 10.6023/cjoc202410012

Abstract( 134) HTML( 2) PDF(627KB)( 178 )

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One-Pot Metal-Free Synthesis of New 1,2,3-Triazolobenzodiaze-pinones by a Sequential Ugi 4CR/Alkyne-Azide Cycloaddition Reaction

Yanmei Yan, Hongli Zhang, Min Yuan, Ruijia Qin, Zhenxing Ren, Yingchun He

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3923-3931 DOI: 10.6023/cjoc202502039

Abstract( 103) HTML( 0) PDF(447KB)( 74 )

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HIGHLIGHTS

Asymmetric Deoxygenative Formal [3＋2] Cycloaddition of Carboxylic Acids and Vinylcyclopropanes

Fangyuan Cheng, Weiping Deng

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3931-3933 DOI: 10.6023/cjoc202500022

Abstract( 39) HTML( 2) PDF(444KB)( 27 )

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Regiodivergent Ligand-Controlled Cobalt-Catalyzed Reductive Hydroxymethylation of Alkynes with Aqueous Formaldehyde

Fu Ye, Weiming Yuan

Chinese Journal of Organic Chemistry 2025, 45 (10), pp 3934-3935 DOI: 10.6023/cjoc202500023

Abstract( 39) HTML( 1) PDF(460KB)( 29 )

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