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化学学报
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化学学报 ›› 1983, Vol. 41 ›› Issue (6): 519-524. 上一篇    下一篇

研究论文

N,N-双-羧 甲基氨基乙酰蛋氨酸的合成及其与铟(III)离子螯合行为的研究

颜庆瑜;蒋凝;邹正国;谢毓元   

  1. 中国科学院上海药物研究所
  • 发布日期:1983-06-15

The synthesis of N, N-bis-carboxymethylamino-acetomethionine and its chelating behaviour with indium (iii)

YAN QINGYU;JIANG NING;ZOU ZHENGGUO;XIE YUYUAN   

  • Published:1983-06-15

PDF

383

被引次数

1

关键词: 酰胺, 甲硫氨酸, 氨三乙酸 P, 螯合剂, 铟离子, 螯合效应

The synthesis of N, N-bis-carboxymethylaminoacetomethionine was described. The acid dissociation constants and the formation constants of its indium (III) chelates at 25`C and \m\=0.1(KNO3) were determined (pka1=2.452, pka2=3.320, pka3=6.799; log KInL=8.90, log KInLi=6.47, log βInLi=15.37) by pH titration method. The hydrolysis constant of the chelate at 30`C was also given. The optimal pH for the formation of normal chelate was calculated to be about 4.8. In addition, the chelate species and coordinated atoms of the ligand were briefly discussed.

Key words: AMIDES, METHIONINE, NITRILOTRISACETIC ACID P, CHELATING AGENT, INDIUM ION, CHELATE EFFECT

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