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Acta Chimica Sinica ›› 2011, Vol. 69 ›› Issue (16): 1946-1950. Previous Articles     Next Articles

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桂皮酸-1,10-二氮杂菲镧配合物的合成及与牛血清白蛋白的相互作用

冯小强*,1，李小芳1，杨声1，伏国庆2   

  1. (1天水师范学院生命科学与化学学院 天水 741001)
    (2天水市中医医院 天水 741001)
  • 投稿日期:2010-08-30 修回日期:2011-04-10 发布日期:2011-04-20
  • 通讯作者: 李小芳 E-mail:lix_f06@lzu.edu.cn

Synthesis and Interaction of Cinnamic Acid-1,10-phenanthroline- La(III) Complexes with Bovine Serum Albumins

Feng Xiaoqiang*,1 Li Xiaofang1 Yang Sheng1 Fu Guoqing2   

  1. (1 College of Life Science and Chemistry, Tianshui Normal University, Tianshui 741001)
    (2 Tianshui Chinese Traditional Hospital, Tianshui 741001)
  • Received:2010-08-30 Revised:2011-04-10 Published:2011-04-20

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Ternary complexes of rare earth, with cinnamic acid and 1,10-phenanthroline were synthesized and characterized. The interaction between ternary complexes and bovine serum albumins (BSA) was studied by ultraviolet spectrum and fluorescence spectrum. Results show that the absorption intensity of BSA increased with the increasing of the concentration of ternary complexes. Ternary complexes quenched the fluorescence of BSA and it was static quenching. The binding constant (KA) and binding sites of ternary complexes with BSA at room temperature were 0.91×105 L•mol－1 and 2.1, respectively.

Key words: cinnamic acid-1,10-phenanthroline-La, BSA, interaction

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