有机化学 ›› 2003, Vol. 23 ›› Issue (7): 717-719. 上一篇    下一篇

研究论文

手性1-β-羧乙基杂氮锗三环类化合物的合成

陶春元;吕群;帅敏   

  1. 九江师范专科学校
  • 发布日期:2003-07-25

Synthesis of Chiral 1-β-Carboxyethylgermatranes

Tao Chunyuan;Lu Qun;Shuai Min   

  1. Jiujiang Teacher's College
  • Published:2003-07-25

采用固相合成的方法,首次合成(4S)-1-β-羧基杂氮锗三环(1),(4S)- 3-甲基-1-β-羧乙基-4-羧基杂氮锗三环(2)和(4S)-1-β-羧乙基- 4-羧基-2-硫代杂氮锗三环(3)。并运用元素分析,~1H NMR,MS进行了表征。

关键词: 固相反应;有机锗化合物;氮杂环化合物;羧基;硫化合物;元素分析, 质子磁共振谱法;质谱法;结构表征

(4S)-l-/?-carboxyethyl-4-carboxylgermatrane (1). (4S )-3-methyl-l- ^-carboxyethyl-4-carboxylgerma-trane (2) and (4S)-l-/3-carboxyethyl-4- carboxyl-2-thiogermatrane (3) were synthesized by solid-state reaction of several L-N, Af-bis(/3-hydroxyethyl) amino-acids with /3- tricHorogermapropanic acid and characterized by elemental analysis, IR, JH NMR and MS spectra.

Key words: SOLID PHASE REACTION;ORGANO GERMANIUM;NITROGEN HETEROCYCLICS;CARBOXY GROUP, SULFUR COMPOUNDS;ELEMENTAL ANALYSIS;1HNMR;MS;STRUCTURE CHARACTERISTICS

中图分类号: