有机化学 ›› 2013, Vol. 33 ›› Issue (04): 657-662.DOI: 10.6023/cjoc201301084 上一篇    下一篇

研究专题

季鏻和金属对高张力六元环的双重稳定化作用

朱从青, 曹晓宇, 夏海平   

  1. 厦门大学化学化工学院 厦门 361005
  • 收稿日期:2013-01-31 修回日期:2013-03-21 出版日期:2013-04-25 发布日期:2013-03-22
  • 通讯作者: 曹晓宇, 夏海平 E-mail:xcao@xmu.edu.cn, hpxia@xmu.edu.cn
  • 基金资助:

    国家重点基础研究发展计划(No. 2012CB821600)、国家自然科学基金(Nos. 21174115, 20925208)及长江学者和创新团队发展计划资助项目.

Double Stabilization of Highly Strained Six-Membered Rings by Phosphonium and Transition Metal

Zhu Congqing, Cao Xiaoyu, Xia Haiping   

  1. College of Chemistry and Chemical Engineering, Xiamen University, Xiamen 361005
  • Received:2013-01-31 Revised:2013-03-21 Online:2013-04-25 Published:2013-03-22
  • Supported by:

    Project supported by the National Basic Research Program of China (No. 2012CB821600), the National Natural Science Foundation of China (Nos. 21174115, 20925208) and the Program for Changjiang Scholars and Innovative Research Team in University.

环炔和环内累积多烯作为有机合成的重要中间体, 在合成化学中扮演着重要的角色. 但是, 对这类高活性物种的稳定化一直是学术界研究的热点和难点. 近年, 我们课题组发现季鏻和过渡金属具有双重稳定化作用, 可以极好地稳定这类高张力环状化合物. 对我们课题组在这方面的最新进展进行了综述.

关键词: 芳炔, 金属杂环, 季鏻, 稳定化, 张力环

Cycloalkynes and cyclocumulenes have attracted considerable attention because they are key intermediates in organic synthesis. Stabilization of these highly active species remains a challenge for synthetic chemists. Recently, we found that phosphonium and transition metal replacement can double stabilize these species. Using this strategy, a series of highly strained six-membered rings with remarkable stability have been synthesized. Herein, the latest progress of our group is reviewed.

Key words: arynes, metallacycles, phosphonium, stabilization, strained rings