有机化学 ›› 2019, Vol. 39 ›› Issue (5): 1411-1416.DOI: 10.6023/cjoc201810010 上一篇    下一篇

研究论文

苯基三氟硼酸钾催化的硅烷还原羰基化合物成醇反应

刘建辉a,b, 王星旸a   

  1. a 大连理工大学精细化工国家重点实验室 大连 116024;
    b 大连理工大学盘锦校区石油与化学工程学院 盘锦 124221
  • 收稿日期:2018-10-11 修回日期:2018-12-12 出版日期:2019-05-25 发布日期:2019-01-18
  • 通讯作者: 刘建辉 E-mail:liujh@dlut.edu.cn
  • 基金资助:

    精细化工国家重点实验室(盘锦)(No.JH2014009)和重点大学基础研究基金资助项目.

Potassium Phenyltrifluoroborate-Catalyzed Reduction of Aldehydes and Ketones into Alcohol with Silanes

Liu Jianhuia,b, Wang Xingyanga   

  1. a State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024;
    b School of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin Campus, Panjin 124221
  • Received:2018-10-11 Revised:2018-12-12 Online:2019-05-25 Published:2019-01-18
  • Contact: 10.6023/cjoc201810010 E-mail:liujh@dlut.edu.cn
  • Supported by:

    Project supported by the State Key Laboratory of Fine Chemicals (Panjin) (No. JH2014009) and the Fundamental Research Funds for the Central Universities.

研究了以有机硅烷为还原剂选择性还原羰基的反应,在2.5 mol% C6H5BF3K,2.2 epuiv.(EtO)3SiH作用下,甲醇为溶剂,室温下将羰基还原为醇.以中等至较高产率得到目标产物.该方法在羰基还原上表现出良好的选择性,为羰基还原提供了一种新的方法.

关键词: 羰基还原, 有机硅烷, 苯基三氟硼酸钾

The selective reduction of carbonyl group with organosilane as reducing agent was studied with methanol as a solvent under the action of 2.5 mol% C6H5BF3K and 2.2 epuiv. (EtO)3SiH. The target products were obtained in medium to high yield. This method shows good selectivity and provides a new method for carbonyl reduction.

Key words: carbonyl reduction, organosilane, potassium phenyl trifluoroborate