Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (5): 875-888.DOI: 10.6023/cjoc201601013 Previous Articles     Next Articles

REVIEW

基于C—H键官能团化/环化串联策略构建吲哚酮分子骨架的研究进展

阿布力米提·阿布都卡德尔a, 张永红a, 张增鹏a, 刘晨江a,b   

  1. a. 新疆大学化学化工学院 乌鲁木齐 830046;
    b. 新疆大学理化测试中心 乌鲁木齐 830046
  • 收稿日期:2016-01-12 修回日期:2016-03-28 出版日期:2016-05-25 发布日期:2016-04-05
  • 通讯作者: 刘晨江 E-mail:pxylcj@126.com
  • 基金资助:

    国家自然科学基金(Nos.21572195,21562039,21502162)资助项目.

Recent Advances of the Access to Indolinones via C—H Bond Functionalization/Cyclization Cascade Strategy

Abdukader Ablimita, Zhang Yonghonga, Zhang Zengpenga, Liu Chenjiang a,b   

  1. a. School of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046;
    b. Physics and Chemistry Detecting Center, Xinjiang University, Urumqi 830046
  • Received:2016-01-12 Revised:2016-03-28 Online:2016-05-25 Published:2016-04-05
  • Supported by:

    Project supported by the National Natural Science Foundation of China (Nos. 21572195, 21562039, 21502162).

Due to the diverse biological activities of indolinones, especially 3,3-disubstituted indolinones, their researches of synthesis have been attracting considerable interest in the areas of organic chemistry. Recently, the radical addition and cyclization reaction of N-arylacrylamides with different radical precursors for the efficient construction of indolinones motifs have attracted much attention. This review summarizes the recent advances of the access to 3,3-disubstituted indolinones based on C—H bond functionalization/cyclization cascade strategy. These reaction mechanisms have also been introduced.

Key words: C—H functionalization, oxindoles, cascade reaction