Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (7): 1636-1642.DOI: 10.6023/cjoc201602007 Previous Articles     Next Articles



张鸣頔, 陈斌, 葛晨, 刘人荣, 高建荣, 贾义霞   

  1. 浙江工业大学化学工程学院 杭州 310014
  • 收稿日期:2016-02-03 修回日期:2016-03-09 发布日期:2016-03-18
  • 通讯作者: 贾义霞
  • 基金资助:


Nickel-Catalyzed Addition and Coupling Reaction of Aryl Triflates to Aldehydes

Zhang Mingdi, Chen Bin, Ge Chen, Liu Renrong, Gao Jianrong, Jia Yixia   

  1. College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014
  • Received:2016-02-03 Revised:2016-03-09 Published:2016-03-18
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21372202) and the Program for New Century Excellent Talents in University (No. NCET-12-1086).

The nickel-catalyzed addition and coupling reaction between aryl triflates and aldehydes were developed. The reactions proceed smoothly in the presence of zinc powder with the use of 10 mol% Ni(dppe)Br2 as a catalyst. A range of aryl methanols and aryl ketones were isolated respectively in moderate to good yields in MeOH and THF solvent via direct addition or coupling reactions. Aliphatic and aromatic aldehydes were involved in this reaction, showing a broad substrate scope.

Key words: transition-metal catalysis, aryl triflate, addition reaction, coupling reaction