Chin. J. Org. Chem. ›› 2016, Vol. 36 ›› Issue (11): 2677-2682.DOI: 10.6023/cjoc201603036 Previous Articles     Next Articles

Articles

硫酸铈介导下黄酮和2-芳基-4-喹啉酮衍生物的合成

刘瑞环a, 王绪礼a, 成飞a, 李福双a, 徐康平a, 谭桂山a,b   

  1. a 中南大学药学院 长沙 410013;
    b 中南大学湘雅医院 长沙 410013
  • 收稿日期:2016-03-22 修回日期:2016-06-20 出版日期:2016-11-25 发布日期:2016-07-08
  • 通讯作者: 徐康平 E-mail:xukp395@csu.edu.cn
  • 基金资助:

    国家自然科学基金(No.31370370)、湖南省科技厅科技计划项目(No.2013SK5077)及海南省社会发展科技专项(No.SF201419)资助项目.

Ce(SO4)2·4H2O Mediated Synthesis of Flavones and 2-Phenyl-4-quinolones

Liu Ruihuana, Wang Xulia, Cheng Feia, Li Fushuanga, Xu Kangpinga, Tan Guishana,b   

  1. a Department of Pharmacy, Central South University, Changsha 410013;
    b Xiangya Hospital, Central South University, Changsha 410013
  • Received:2016-03-22 Revised:2016-06-20 Online:2016-11-25 Published:2016-07-08
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No.31370370),the Science and Technology Planning Project of Hunan Pprovince (No.2013SK5077) and the Social Development of Science and Technology Project of Hainan Province (No.SF201419)

A simple and powerful procedure for the synthesis of flavones and quinolones was developed by using Ce(SO4)2·4H2O as oxidant, readily available 2'-hydroxychalcones and 2'-aminochalcones as raw materials, and dimethyl sulfoxide (DMSO) as solvent at 110℃. The new procedure is characterized with raw material easy to get, low manufacturing cost, mild reaction condi-tions and high yields.

Key words: Ce(SO4)2·, 4H2O, 2'-hydrochalcone, 2'-aminochalcone, flavone, quinolone