Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (12): 4071-4086.DOI: 10.6023/cjoc202004047 Previous Articles     Next Articles


董道青a, 孙媛媛a, 李光辉a, 杨欢a, 王祖利a, 徐鑫明b   

  1. a 青岛农业大学化学与药学院 山东青岛 266109;
    b 烟台大学化学化工学院 山东烟台 264005
  • 收稿日期:2020-04-29 修回日期:2020-06-30 发布日期:2020-07-17
  • 通讯作者: 王祖利
  • 基金资助:

Recent Progress in the Functionalization of Quinoline N-Oxide

Dong Daoqinga, Sun Yuanyuana, Li Guanghuia, Yang Huana, Wang Zulia, Xu Xinmingb   

  1. a College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, Shandong 266109;
    b College of Chemistry and Chemical Engineering, Yantai University, Yantai, Shandong 264005
  • Received:2020-04-29 Revised:2020-06-30 Published:2020-07-17
  • Supported by:
    Project supported by the National Natural Science Foundation of China (No. 21772107) and the Key Research and Development Plan of Shandong Province (No. 2019GSF108017).

Owning to their low cost and readily available, quinoline N-oxides are widely used in organic synthesis. The functionalization reactions of C(2) and C(8) position of quinoline N-oxides and the reaction mechanisms of these reactions are summaried. It will be helpful for the reaction of quinoline N-oxide in the future.

Key words: quinolone N-oxide, nitrogen compounds, functionalization, reaction mechanism