Chinese Journal of Organic Chemistry ›› 2019, Vol. 39 ›› Issue (11): 3114-3131.DOI: 10.6023/cjoc201903029 Previous Articles     Next Articles

Special Issue: 碳氢活化合辑2018-2019

导向基团辅助过渡金属催化间位碳氢官能化研究进展

吴梅a*(), 黄新平b, 张海兵a, 李鹏飞a   

  1. a中国石油大学(北京)克拉玛依校区 重质油国家重点实验室 新疆克拉玛依 834000
    b 中石油克拉玛依石化有限责任公司 新疆克拉玛依 834000
  • 收稿日期:2019-03-15 出版日期:2019-11-01 发布日期:2019-06-19
  • 通讯作者: 吴梅 E-mail:wumei_1121@163.com
  • 基金资助:
    中国石油大学(北京)克拉玛依校区科研启动(RCYJ2016B-03-003)

Advances on Directing-Group Assisted meta-C-H Functionalization Catalyzed by Transition Metal

Wu Meia*(), Huang Xinpingb, Zhang Haibinga, Li Pengfeia   

  1. a State Key Laboratory of Heavy Oil Processing, China University of Petroleum-Beijing At Karamay, Karamay, Xingjiang 834000
    b Petrochina Karamay Petrochemical CO. LTD, Karamay, Xingjiang 834000
  • Received:2019-03-15 Online:2019-11-01 Published:2019-06-19
  • Contact: Wu Mei E-mail:wumei_1121@163.com
  • Supported by:
    the Science Foundation of China University of Petroleum-Beijing at Karamay(RCYJ2016B-03-003)

Transition-metal-catalyzed functionalization of unactivated C-H bonds is a highly attractive strategy for the synthesis of organic molecules, however, regioselective control is a central challenge in this field. The directing group assisted C-H functionalizations such as the use of directing templates and transient mediator, secondary interaction have attracted more attentions from researchers. The meta-C-H functionalizatioin assisted by directing groups are summarized in details. The existing problems and limitations of this field are also included. Finally, the development trend of this area is prospected.

Key words: directed by template, meta-activation, C-H functionalization, secondary interaction, transient mediator