Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (10): 3044-3064.DOI: 10.6023/cjoc202005095 Previous Articles     Next Articles


姚彪, 巫佳浩, 汪钰, 江焕峰   

  1. 华南理工大学化学与化工学院 广东省功能分子工程重点实验室 广州 510641
  • 收稿日期:2020-05-31 修回日期:2020-07-06 发布日期:2020-08-11
  • 通讯作者: 江焕峰
  • 基金资助:

Methods of Transition Metal-Catalyzed Asymmetric Oxidation

Yao Biao, Wu Jiahao, Wang Yu, Jiang Huanfeng   

  1. Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641
  • Received:2020-05-31 Revised:2020-07-06 Published:2020-08-11
  • Supported by:
    Project supported by the National Key Research and Development Program of China (No. 2016YFA06002900) and the Key Research and Development Program of Guangdong Province (No. 2020B010188001).

Transition metal-catalyzed asymmetric oxidation, as one of important research targets of chiral synthesis, provides a direct, practical route for the synthesis of various chiral bioactive products and drugs, and has received much attention. The recent progress of the methods of transition metal-catalyzed asymmetric oxidation, especially, asymmetric oxidative functionalization of olefins, C-H bond asymmetric oxidation reaction, asymmetric BV oxidation and sulfide asymmetric oxidation is elaborated. Outlook of those issuesis is also discussed.

Key words: transition metal catalysis, asymmetric oxidation, enantioselectivity, olefin, C-H activation