Chinese Journal of Organic Chemistry ›› 2022, Vol. 42 ›› Issue (7): 1904-1924.DOI: 10.6023/cjoc202202005 Previous Articles     Next Articles



毛沅浩a, 高延峰a, 苗志伟a,b,*()   

  1. a南开大学化学学院 元素有机化学国家重点实验室 天津 300071
    b天津化学化工协同创新中心 天津 300071
  • 收稿日期:2022-02-06 修回日期:2022-03-23 发布日期:2022-08-09
  • 通讯作者: 苗志伟
  • 基金资助:
    国家自然科学基金(22071113); 天津市重点研发计划(19YFZCSN00240)

Research Progress on the Asymmetric Cyclization Synthesis of Seven-Membered Rings via Transition Metal Catalysis

Yuanhao Maoa, Yanfeng Gaoa, Zhiwei Miaoa,b()   

  1. aState Key Laboratory and Institute of Elemento-Organic Chemistry, College of Chemistry, Nankai University, Tianjin 300071
    bCollaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071
  • Received:2022-02-06 Revised:2022-03-23 Published:2022-08-09
  • Contact: Zhiwei Miao
  • Supported by:
    National Natural Science Foundation of China(22071113); Key Technologies R & D Program of Tianjin City(19YFZCSN00240)

Seven-membered ring skeletons widely exist in many natural products and drug molecules, and it is of great significance to develop efficient asymmetric synthesis methods for seven-membered ring compounds. The progress in the asymmetric synthesis of seven-membered ring compounds by transition metal-catalyzed cycloaddition reactions since 2000 is reviewed. The future development direction of this field is also prospected.

Key words: transition metal catalysis, asymmetric synthesis, seven-membered ring compound