Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (9): 3366-3378.DOI: 10.6023/cjoc202105015 Previous Articles     Next Articles



赵喜a, 区颖聪a, 刘艳a, Keiji Maruokab, 陈迁a,*()   

  1. a 广东工业大学轻工化工学院 广州 510006
    b 京都大学药学院 京都 606-8501 日本
  • 收稿日期:2021-05-10 修回日期:2021-06-08 发布日期:2021-07-05
  • 通讯作者: 陈迁
  • 基金资助:
    广东省科技计划(2021A0505030069); 广东工业大学青年百人计划(220413506)

Recent Progress in the Construction of S—S, P—S and C—S Bonds Involving O2-Initiated Sulfur-Centered Radicals

Xi Zhaoa, Yingcong Oua, Yan Liua, Keiji Maruokab, Qian Chena()   

  1. a School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, China
    b Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo, Kyoto 606-8501, Japan
  • Received:2021-05-10 Revised:2021-06-08 Published:2021-07-05
  • Contact: Qian Chen
  • Supported by:
    Science and Technology Planning Project of Guangdong Province(2021A0505030069); 100 Young Talents Program of Guangdong University of Technology(220413506)

Sulfur-containing organic compounds have been widely used in organic synthesis, pharmaceuticals, pesticides and functional materials. Thus, the development of green, mild and highly efficient methodologies for the synthesis of organosulfur compounds is of great importance. Some sulfur-containing compounds can be directly initiated by O2 as the ideal green oxidant to generate sulfur-centered radicals, and the corresponding radical reactions provide a novel approach to the construction of S—S, P—S and C—S bonds. These reactions can be performed under mild conditions without the use of toxic reagents, transition metals and strong oxidants. In this review, the recent progress in the construction of S—S, P—S and C—S bonds involving O2-initiated sulfur-centered radicals is introduced on the basis of different reaction types.

Key words: oxygen, sulfur-centered radicals, organosulfur compounds, radical reactions