Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (12): 4808-4814.DOI: 10.6023/cjoc202107021 Previous Articles     Next Articles

ARTICLES

无光催化剂条件下紫外光引发芳基醛或芳基酮与炔烃环化反应构筑茚酮化合物

肖玉娟a, 杨阳a, 张凡b, 冯亚栋a,b,*(), 崔秀灵b,*()   

  1. a 厦门华厦学院环境与公共健康学院 检测技术和智能仪器研究所 厦门 361024
    b 华侨大学生物医学学院 分子药物教育部工程研究中心 福建省分子医学重点实验室 福建省高校精准医学与分子诊断重点实验室 厦门市海洋与基因药物重点实验室 厦门 361021
  • 收稿日期:2021-07-07 修回日期:2021-07-29 发布日期:2021-08-09
  • 通讯作者: 冯亚栋, 崔秀灵
  • 基金资助:
    福建省中青年教师教育科研(JAT190990)

UV-Light-Initiated Construction of Indenones through Cyclization of Aryl Aldehydes or Aryl Ketones with Alkynes Avoiding Photocatalyst

Yujuan Xiaoa, Yang Yanga, Fan Zhangb, Yadong Fenga,b(), Xiuling Cuib()   

  1. a College of Environment and Public Health, Institute of Analytical Technology and Smart Instruments, Xiamen Huaxia University, Xiamen 361024
    b Engineering Research Center of Molecular Medicine, Ministry of Education, Key Laboratory of Fujian Molecular Medicine, Key Laboratory of Precision Medicine and Molecular Diagnosis of Fujian Universities, Key Laboratory of Xiamen Marine and Gene Drugs, School of Biomedical Sciences, Huaqiao University, Xiamen 361021
  • Received:2021-07-07 Revised:2021-07-29 Published:2021-08-09
  • Contact: Yadong Feng, Xiuling Cui
  • Supported by:
    Fujian Education and Scientific Research Project for Young and Middle-aged Teachers(JAT190990)

The first UV-light-initiated cyclization of aryl aldehydes or aryl ketones with alkynes has been developed for the preparation of indenones. This reaction could proceed smoothly under UV-light with O2 as an oxidant and photocatalyst-free condition, which features high efficiency, high atom economy, easily available starting materials, environmental friendliness, and tolerance to broad functional groups.

Key words: UV-light, cyclization, photocatalyst-free, indenones