Chinese Journal of Organic Chemistry ›› 2021, Vol. 41 ›› Issue (12): 4575-4587.DOI: 10.6023/cjoc202109008 Previous Articles     Next Articles

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α-酮酸在无金属有机光合成中的应用

谢坤宸, 江铭轩, 陈晓岚, 吕琪妍*(), 於兵*()   

  1. 郑州大学化学学院 绿色催化中心 郑州 450001
  • 收稿日期:2021-09-04 修回日期:2021-10-13 发布日期:2021-10-20
  • 通讯作者: 吕琪妍, 於兵
  • 作者简介:
    † 共同第一作者
  • 基金资助:
    国家自然科学基金(21971224); 国家自然科学基金(22171249); 大学生创新创业训练计划(S202110459196); 大学生创新创业训练计划(2021cxcy197); 郑州大学本科生拔尖计划资助项目

Application of α-Keto Acids in Metal-Free Photocatalysis

Kunchen Xie, Mingxuan Jiang, Xiaolan Chen, Qiyan Lü(), Bing Yu()   

  1. College of Chemistry, Zhengzhou University, Zhengzhou 450001
  • Received:2021-09-04 Revised:2021-10-13 Published:2021-10-20
  • Contact: Qiyan Lü, Bing Yu
  • About author:
    † These authors contributed equally to this work.
  • Supported by:
    National Natural Science Foundation of China(21971224); National Natural Science Foundation of China(22171249); Innovation and Entrepreneurship Training Program(S202110459196); Innovation and Entrepreneurship Training Program(2021cxcy197); Top Undergraduates Program of Zhengzhou University

As a carboxylic acid, α-keto acid can be used as an acylating reagent by decarboxylation in organic synthesis. However, traditional methods often need transition metal catalysts or high temperatures, which limits the application of α-keto acid to a certain extent. In recent years, organic transformations induced by visible light have attracted extensive attention due to its mild conditions and simple operations. Herein, the recent advances of metal-free photocatalytic application of α-keto acids are summarized, which mainly include acylation reactions and cyclization reactions.

Key words: α-keto acid, visible light, metal-free catalysis, acylation