Chinese Journal of Organic Chemistry ›› 2023, Vol. 43 ›› Issue (6): 2096-2103.DOI: 10.6023/cjoc202212002 Previous Articles     Next Articles


黄丽珠a, 刘云云a,*(), 万结平a,b,*()   

  1. a 江西师范大学化学化工学院 国家单糖化学合成工程技术研究中心 南昌 330022
    b 南京林业大学林产化学与材料国际创新高地 南京 210037
  • 收稿日期:2022-12-03 修回日期:2023-01-06 发布日期:2023-01-18
  • 基金资助:

Engineering Biomass Feedstock Cyrene to Value-Added Compounds by Enaminone Platform Construction

Lizhu Huanga, Yunyun Liua,*(), Jieping Wana,b,*()   

  1. a National Engineering Research Center for Carbohydrate Synthesis, College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022
    b International Innovation Center for Forest Chemicals and Materials, Nanjing Forestry University, Nanjing 210037
  • Received:2022-12-03 Revised:2023-01-06 Published:2023-01-18
  • Contact: E-mail:;
  • Supported by:
    National Natural Science Foundation of China(22161022)

The enamination of Cyrene in the ketone α-site leading to the enamino Cyrene (EC) has been developed. The practical preparation of EC as a platform synthon opens broad space of chemical transformation for Cyrene biomass feedstock in the synthesis of diverse value-added chemicals. In the present work, the transformation of the EC for the synthesis of many different chiral organic derivatives, including NH-/N,N-disubstituted ECs, the cyanoalkenyl- and vinyl phosphine oxide-elabo- rated Cyrene, Cyrene fused furan, and 2,2-difluorodihydrofuran fused Cyrene, has been realized.

Key words: Cyrene, biomass feedstock, enamination, platform, value-added